Nanostructured materials detect epidermal growth factor receptor, neuron specific enolase and carcinoembryonic antigen
Nanoscale Pub Date: 2015-09-09 DOI: 10.1039/C5NR04476F
Abstract
New nanostructured materials based on thin films of Cu and Ni deposited on textile material (veil), as well as gold nanostructured microspheres were used for the design of new stochastic sensors. The stochastic sensors were able to detect simultaneously a panel of biomarkers comprising epidermal growth factor receptor, neuron specific enolase, and carcinoembryonic antigen from whole blood samples with high reliabilities – recovery tests higher than 97.00%, with a RSD (%) lower than 0.1%. The stochastic sensors had shown high sensitivities and low determination levels for the detection of the proposed panel of biomarkers making early detection of lung cancer possible by fast screening of whole blood.
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Journal Name:Nanoscale
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CAS no.: 89640-58-4