Iron-catalyzed cross-dehydrogenative C–H amidation of benzofurans and benzothiophenes with anilines?
Organic Chemistry Frontiers Pub Date: 2021-01-29 DOI: 10.1039/D0QO01651A
Abstract
An efficient iron-catalyzed cross-dehydrogenative aromatic C–H amidation using DDQ as an oxidant under mild conditions is reported, providing a straightforward access to structurally diverse diarylamine derivatives incorporating benzofuran/benzothiophene motifs. Mechanistic studies indicated that a nitrogen-centered anilino radical is involved in the C–N bond formation.
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Journal Name：Organic Chemistry Frontiers
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CAS no.: 89640-58-4
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