Nickel catalyzed intramolecular oxidative coupling: synthesis of 3-aryl benzofurans?
RSC Advances Pub Date: 2020-06-10 DOI: 10.1039/D0RA03071F
Abstract
Recent research has been focused on the transition metal-catalyzed reactions. Herein we have developed nickel-catalyzed synthesis of 3-aryl benzofurans from ortho-alkenyl phenols via intramolecular dehydrogenative coupling. Notably, simple O2 gas served as an oxidant, without using any sacrificial hydrogen acceptor. The strategy enabled the synthesis of 3-aryl benzofurans in good to excellent yields.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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