A palladium-catalyzed cascade process for spirooxindole: an alternative way for the synthesis of spiro(indoline-3,2′-quinazolin)-2-ones?
Organic & Biomolecular Chemistry Pub Date: 2021-02-09 DOI: 10.1039/D0OB02580A
Abstract
A palladium-catalyzed cascade strategy has been developed for one-pot synthesis of functionalized spiro(indoline-3,2′-quinazolin)-2-one derivatives from readily available starting materials. The reaction proceeds via C–C and two C–N bond formations in a single reaction operation. This method offers an attractive pathway for the synthesis of a broad range of spiro(indoline-3,2′-quinazolin)-2-ones in good yields.
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Journal Name:Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4