Intramolecular decarboxylative coupling as the key step in copper-catalyzed domino reaction: facile access to 2-(1,3,4-oxadiazol-2-yl)aniline derivatives?
Chemical Communications Pub Date: 2015-03-05 DOI: 10.1039/C5CC01116G
Abstract
A copper-catalyzed domino protocol for the synthesis of 2-(1,3,4-oxadiazol-2-yl)aniline derivatives has been developed from simple and available isatins and hydrazides. This domino process integrated consecutive condensation, base-promoted ring-opening and the key copper-catalyzed decarboxylative coupling for intramolecular C–O bond formation.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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