Lipase-catalyzed regioselective acylation of sugar in microreactors?

RSC Advances Pub Date: 2012-02-10 DOI: 10.1039/C2RA01112C

Abstract

The highly regioselective synthesis of sugar 6-monoesters with sugar and vinyl carboxylate in a flow microreactor using Lipozyme TL IM from Thermomyces lanuginosus as a catalyst has been developed. The important features of this method include mild reaction conditions, short reaction times (30 min), high yields and high regioselectivities.

Graphical abstract: Lipase-catalyzed regioselective acylation of sugar in microreactors
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