Mirror symmetry breaking and chiral amplification in foldamer-based supramolecular helical aggregates?

Chemical Communications Pub Date: 2012-01-10 DOI: 10.1039/C2CC16266K

Abstract

Spontaneous asymmetric generation of supramolecular chiral fibers was observed in the folding induced self-assembly of a lock-washer shaped foldamer. A secondary nucleation growth mechanism is proposed to explain the observed chiral amplification or deracemization of these supramolecular fibers.

Graphical abstract: Mirror symmetry breaking and chiral amplification in foldamer-based supramolecular helical aggregates
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