Metal-free thioesterification of amides generating acyl thioesters?

New Journal of Chemistry Pub Date: 2019-05-16 DOI: 10.1039/C9NJ01748H

Abstract

A base-initiated thioesterification of amides with various thiols is reported. This reaction can take place efficiently under metal-free and air-atmospheric conditions, and provides a facile and practically useful approach to the synthesis of valuable acyl thioesters.

Graphical abstract: Metal-free thioesterification of amides generating acyl thioesters
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