Lactone synthesis activity in a site-directed mutant of an extradiol catechol dioxygenase enzyme

Chemical Communications Pub Date: 2004-12-14 DOI: 10.1039/B414292F

Abstract

A H115Y site-directed mutant of extradiol catechol dioxygenase MhpB catalyses an intramolecular lactonisation reaction upon its natural substrate.

Graphical abstract: Lactone synthesis activity in a site-directed mutant of an extradiol catechol dioxygenase enzyme
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