Iodine-mediated aminosulfonylation of alkenyl sulfonamides with sulfonyl hydrazides: synthesis of sulfonylmethyl piperidines, pyrrolidines and pyrazolines?
Organic & Biomolecular Chemistry Pub Date: 2019-09-27 DOI: 10.1039/C9OB01847F
Abstract
An aminosulfonylation of alkenyl sulfonamides was reported. Using iodine as the catalyst, TBHP as the oxidant, and sulfonyl hydrazides as the sulfonyl radical sources, a variety of sulfonylmethyl piperidines, pyrrolidines and pyrazolines were obtained in moderate to excellent yields.
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Journal Name:Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4