10 gram-scale synthesis of a chiral oxazoline iminopyridine ligand and its applications?

Organic Chemistry Frontiers Pub Date: 2017-10-20 DOI: 10.1039/C7QO00816C

Abstract

This method reports on the preparation of the chiral oxazoline iminopyridine (OIP) ligand and its applications in the asymmetric hydroboration and hydrosilylation of 1,1-disubstituted alkenes. These reactions could be carried out on a scale of 10 grams.

Graphical abstract: 10 gram-scale synthesis of a chiral oxazoline iminopyridine ligand and its applications
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