In situ generation of ammonia for the copper-catalyzed synthesis of primary aminoquinolines
New Journal of Chemistry Pub Date: 2014-03-03 DOI: 10.1039/C4NJ00046C
Abstract
The synthesis of primary aminoquinolines from iodoquinolines was carried out in the presence of copper(I) iodide and formamide as the solvent and source of ammonia generated in situ. The reaction proceeded under mild conditions within a few hours and was applicable to various iodoquinolines.
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Journal Name:New Journal of Chemistry
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CAS no.: 89640-58-4