Gas-chromatographic determination of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (methyl-CCNU). Part I. Cyclisation to a substituted aminooxazoline

ANALYSTANALYST Pub Date: DOI: 10.1039/AN9820700301

Abstract

Methods for the gas-chromatographic determination of methyl-CCNU employing cyclisation to the substituted aminooxazoline have been explored. These procedures were found to be unsatisfactory for the determination of the drug in body fluids.

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