Formal total synthesis of selaginpulvilin D?
Organic & Biomolecular Chemistry Pub Date: 2017-05-11 DOI: 10.1039/C7OB00950J
Abstract
An efficient and mild synthetic strategy for the total synthesis of selaginpulvilin D has been reported. A highly chemoselective enyne–alkyne dehydro Diels–Alder reaction has been employed for the construction of the tricyclic fluorene framework present in the natural product selaginpulvilin D. An improved overall yield (10.5%) has been achieved for selaginpulvilin D, starting from commercially available m-anisaldehyde in 9 linear, operationally simple synthetic transformations.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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