Engineering stereocontrol into an aldolase-catalysed reaction?

Chemical Communications Pub Date: 2004-11-23 DOI: 10.1039/B413255F

Abstract

A novel thermostable aldolase has been developed for synthetic application, and substrate engineering has been used to induce stereocontrol into aldol reactions of this naturally-promiscuous enzyme.

Graphical abstract: Engineering stereocontrol into an aldolase-catalysed reaction
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