Divergent synthesis of N-heterocycles by Pd-catalyzed controllable cyclization of vinylethylene carbonates?
Chemical Communications Pub Date: 2018-10-02 DOI: 10.1039/C8CC06945J
Abstract
Here, we report a palladium-catalyzed controllable cyclization of vinyl ethylene carbonates that proceeds through formal migration [2+3] and [5+2] cycloadditions, respectively, under mild conditions. The transformation described here affords a series of synthetically versatile 5,7-membered N-heterocycles which are found in natural products and pharmaceuticals with biological and medicinal properties.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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