A highly selective and fast-response fluorescent probe for visualization of enzymatic H2S production in vitro and in living cells?

Chemical Communications Pub Date: 2015-05-19 DOI: 10.1039/C5CC03707G

Abstract

An o-fluorinated-azido-capped rhodamine probe can react with H2S efficiently and selectively to give large off–on fluorescence enhancement. The probe was used to develop an assay for cystathionine β-synthase acitivity and for in situ visualization of endogenously produced H2S in living cells.

Graphical abstract: A highly selective and fast-response fluorescent probe for visualization of enzymatic H2S production in vitro and in living cells
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