Diastereotopic group selective intramolecular cycloadditions of sulfenic acids to 1,4-dienes?

Organic & Biomolecular Chemistry Pub Date: 2003-12-01 DOI: 10.1039/B314176D

Abstract

The ratio of diastereomeric cis-fused perhydrobenzothiophene S-oxides formed via the intramolecular addition of a sulfenic acid to a 1,4-diene is controlled by the nature of the protecting group on a chiral alcohol in the connecting chain.

Graphical abstract: Diastereotopic group selective intramolecular cycloadditions of sulfenic acids to 1,4-dienes
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