DNA molecular recognition of intercalators affects aggregation of a thermoresponsive polymer?

Polymer Chemistry Pub Date: 2014-05-07 DOI: 10.1039/C4PY00600C

Abstract

Binding of intercalators to dsDNA switches the aggregation phenomena of DNA–PNIPAM because the binding decreases the dsDNA conformational entropy and/or the shielding of dsDNA charges. Thus, dsDNA–PNIPAM was dramatically aggregated in response to molecular recognition of the DNA–intercalator.

Graphical abstract: DNA molecular recognition of intercalators affects aggregation of a thermoresponsive polymer
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