Discovery of a new fluorescent light-up probe specific to parallel G-quadruplexes?
Chemical Communications Pub Date: 2014-08-21 DOI: 10.1039/C4CC05394J
Abstract
A novel 2,4,5-triaryl-substituted imidazole (IZCM-1) has been found to display distinct and specific fluorescence enhancement upon binding to parallel G-quadruplexes. Such a sensitive and topology-specific probe is able to light up without affecting the topology or thermal stability of the G-quadruplex sample. Thus, these advantages distinguish IZCM-1 from other G-quadruplex probes.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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