De novo endo-functionalized organic cages as cooperative multi-hydrogen-bond-donating catalysts?

Chemical Communications Pub Date: 2017-03-07 DOI: 10.1039/C7CC00938K

Abstract

Two endo-functionalized organic cages as oxyanion hole mimics were achieved via dynamic covalent chemistry, which exhibit good size selectivity, catalytic activity and broad substrate scopes for Friedel–Crafts reactions. The modular character of the synthesis provides an easy way to modify the size, shape and inner function of the molecular cavity.

Graphical abstract: De novo endo-functionalized organic cages as cooperative multi-hydrogen-bond-donating catalysts
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