Copper-catalyzed aerobic oxygenative cross dehydrogenative coupling of methyl ketones with para-C–H of primary anilines?

Green Chemistry Pub Date: 2016-11-11 DOI: 10.1039/C6GC02271E

Abstract

A novel oxygenative cross dehydrogenative coupling of methyl ketones with para-C–H of primary anilines under a copper/oxygen catalytic system is described. This methodology features advantages including readily available starting materials, green oxidant, and broad functional group tolerance.

Graphical abstract: Copper-catalyzed aerobic oxygenative cross dehydrogenative coupling of methyl ketones with para-C–H of primary anilines
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