Catalytic amounts of triarylaminium salt initiated aerobic oxidative coupling of N-aryl tetrahydroisoquinolines?

Organic & Biomolecular Chemistry Pub Date: 2014-03-12 DOI: 10.1039/C3OB42454E

Abstract

A novel stable radical cation triarylaminium salt able to induce aerobic oxidative α-C–H functionalization of tertiary amines in catalytic amounts has been developed. The reaction is performed in the absence of any other additives under mild conditions and only requires atmosphere air as a sustainable co-oxidant.

Graphical abstract: Catalytic amounts of triarylaminium salt initiated aerobic oxidative coupling of N-aryl tetrahydroisoquinolines
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