Catalyst-free, one-pot three-component 1,3-dipolar cycloaddition of diethyl 2-aminomalonate, benzaldehydes and 3-nitro-2H-chromenes?

RSC Advances Pub Date: 2012-11-29 DOI: 10.1039/C2RA23035F

Abstract

An one-pot efficient diastereoselective 1,3-dipolar cycloaddition of diethyl 2-aminomalonate, benzaldehydes and 3-nitro-2H-chromenes has been developed. Catalyst-free conditions, facile procedure and high yields of the polysubstituted benzopyrano[3,4-c]-pyrrolidines are the salient features of this methodology.

Graphical abstract: Catalyst-free, one-pot three-component 1,3-dipolar cycloaddition of diethyl 2-aminomalonate, benzaldehydes and 3-nitro-2H-chromenes
Recommended Literature