Serotonins
Serotonin is a monoamine neurotransmitter that plays a crucial role in the human body and brain, influencing various physiological processes including mood regulation, sleep, appetite, and pain perception. This naturally occurring chemical is synthesized from tryptophan through a series of enzymatic reactions. In the central nervous system (CNS), serotonin modulates neuronal activity by binding to specific receptors, thereby affecting emotional states and behaviors. Serotonin also functions as a key component in the peripheral nervous system, contributing to vascular tone regulation and gastric motility.
In pharmaceutical applications, serotonin is a target for several drugs used in treating depression, anxiety disorders, and certain types of migraines. Additionally, selective serotonin reuptake inhibitors (SSRIs) are widely prescribed antidepressants that work by increasing the levels of serotonin available in the brain. The study of serotonin continues to expand our understanding of neuropsychiatric conditions, making it a vital area of research in both academic and clinical settings.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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5-Hydroxytryptamine; Nb-(3-Hydroxy-4-methoxy-E-cinnamoyl) | 444105-65-1 | C20H20N2O4 |
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5-Hydroxytryptamine; Nb-(4-Methoxy-E-cinnamoyl) | 570411-28-8 | C20H20N2O3 |
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207386-94-5 | C11H14N2O4 | |
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Mucronatin B | 1562052-77-0 | C21H23N3O3 |
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5-Hydroxy Tryptophan | 56-69-9 | C11H12N2O3 |
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1H-Indol-5-ol, 3-(2-aminopropyl)-, (S)- | 95114-43-5 | C11H14N2O |
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L-Tryptophan, 5-hydroxy-, ethyl ester | 36892-61-2 | C13H16N2O3 |
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bufobutanoic acid methyl ester | 284028-38-2 | C15H18N2O4 |
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N-Boc-5-hydroxytryptophan Methyl Ester | 203736-17-8 | C17H22N2O5 |
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BOC-5-BENZYLOXY-DL-TRYPTOPHAN | 1219197-92-8 | C23H26N2O5 |
Related Literature
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Shaun D. Wong,Edward I. Solomon Dalton Trans., 2014,43, 17567-17577
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Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
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Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
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Chen-Yu Chien,Sheng-Sheng Yu Chem. Commun., 2020,56, 11949-11952
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Liao Xiaoqing,Li Ruiyi,Li Zaijun,Sun Xiulan,Wang Zhouping,Liu Junkang New J. Chem., 2015,39, 5240-5248
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