Phenylacetamides
Phenylacetamides are a class of organic compounds characterized by the presence of an acetamide group attached to a phenyl ring. These compounds exhibit diverse biological activities, making them significant in various applications. Structurally, they consist of an aromatic benzene ring with an acetylamine moiety (-CO-NH-) attached to one of its carbon atoms.
Phenylacetamides are used in the pharmaceutical industry as precursors for drug synthesis due to their potential for medicinal applications. They also find utility in agricultural chemicals, where their ability to act as herbicides or fungicides is leveraged. Additionally, these compounds have found use in the formulation of materials and adhesives owing to their chemical versatility.
The preparation of phenylacetamides typically involves reactions such as Friedel-Crafts acylation followed by alkylation or amidation. Their synthetic nature allows for modification of functional groups, thereby tailoring their properties to specific applications.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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Benzeneacetamide,4-ethoxy-a-[4-(4-ethoxyphenyl)-3-hydroxy-5-oxo-2(5H)-furanylidene]-N-2-thiazolyl-,(E)- (9CI) | 59522-44-0 | C25H22N2O6S |
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Benzeneacetamide,2,4-dichloro- | 55954-27-3 | C8H7Cl2NO |
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3-hydroxy-2-phenylpropanamide | 56598-62-0 | C9H11NO2 |
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Benzeneacetamide,3,4-dihydroxy- | 1129-53-9 | C8H9NO3 |
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Benzeneacetic acid, 2-(aminocarbonyl)hydrazide | 15129-13-2 | C9H11N3O2 |
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Benzeneacetamide,N-hydroxy-3,4,5-trimethoxy- | 22372-34-5 | C11H15NO5 |
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(S)-Mandelamide | 24008-63-7 | C8H9NO2 |
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1-(Phenylacetyl)piperidine-4-carboxylic Acid | 26965-32-2 | C14H17NO3 |
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N-Benzyl-2-chloro-2-phenylacetamide | 27946-19-6 | C15H14ClNO |
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2-Thiopheneacetamide, a-hydroxy-N-methyl-N-[2-(4-morpholinyl)ethyl]-a-phenyl-, hydrochloride (1:1) | 37109-12-9 | C19H25ClN2O3S |
Related Literature
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José M. Rivera,Mariana Martín-Hidalgo,Jean C. Rivera-Ríos Org. Biomol. Chem., 2012,10, 7562-7565
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Chongyang Zhu,Xiaojia Bian,Xin Jia,Ning Tang,Yongqiang Cheng Food Funct., 2020,11, 10635-10644
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Lei Yang,Yuan Zeng,Haibo Wu,Chunwu Zhou,Lei Tao J. Mater. Chem. B, 2020,8, 1383-1388
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Eunhak Lim,Jiyoung Heo,Seong Keun Kim Nanoscale, 2019,11, 11369-11378
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