Phenylacetamides
Phenylacetamides are a class of organic compounds characterized by the presence of an acetamide group attached to a phenyl ring. These compounds exhibit diverse biological activities, making them significant in various applications. Structurally, they consist of an aromatic benzene ring with an acetylamine moiety (-CO-NH-) attached to one of its carbon atoms.
Phenylacetamides are used in the pharmaceutical industry as precursors for drug synthesis due to their potential for medicinal applications. They also find utility in agricultural chemicals, where their ability to act as herbicides or fungicides is leveraged. Additionally, these compounds have found use in the formulation of materials and adhesives owing to their chemical versatility.
The preparation of phenylacetamides typically involves reactions such as Friedel-Crafts acylation followed by alkylation or amidation. Their synthetic nature allows for modification of functional groups, thereby tailoring their properties to specific applications.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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Benzeneacetamide, N-octyl- | 57772-71-1 | C16H25NO |
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Benzeneacetamide, N-(2-methylpropyl)- | 62856-00-2 | C12H17NO |
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Benzeneacetamide,N-hydroxy-N-methyl- | 72229-75-5 | C9H11NO2 |
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2-Thiopheneacetamide,N-[2-(dimethylamino)ethyl]-a-hydroxy-N-methyl-a-phenyl-, hydrochloride (1:1) | 37109-10-7 | C17H23ClN2O2S |
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4-Fluorophenylacetic hydrazide | 34547-28-9 | C8H9FN2O |
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N-(3-Cyanophenyl)benzeneacetamide | 89246-40-2 | C15H12N2O |
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N-(2,2-Dimethoxyethyl)-2-phenylacetamide | 89314-87-4 | C12H17NO3 |
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Propanediamide, 2-ethyl-2-phenyl-, hydrate (1:1) | 80866-90-6 | C11H16N2O3 |
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N-(4-Cyanophenyl)-2-(4-hydroxyphenyl)acetamide | 886362-48-7 | C15H12N2O2 |
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N-(3-Cyanophenyl)-2-(4-hydroxyphenyl)acetamide | 886362-51-2 | C15H12N2O2 |
Related Literature
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Vishwesh Venkatraman,Marco Foscato,Vidar R. Jensen,Bj?rn K?re Alsberg J. Mater. Chem. A, 2015,3, 9851-9860
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Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
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Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245
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Liao Xiaoqing,Li Ruiyi,Li Zaijun,Sun Xiulan,Wang Zhouping,Liu Junkang New J. Chem., 2015,39, 5240-5248
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Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
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