L-alpha-amino acids
L-α-Amino acids are a class of amino acids that possess an α-carbon atom bonded to the amine group (NH?) and the carboxylic acid group (COOH), with the hydrogen atom and the side chain (R-group) attached to the same carbon. These amino acids play crucial roles in biological processes, particularly as building blocks for proteins. The L-stereoisomer is the most common form found in natural proteins, whereas D-α-amino acids are less prevalent but still occur in certain peptide structures.
The α-carbon of L-α-amino acids is asymmetric (except glycine), meaning it can exist in two enantiomeric forms—L and D. However, only the L-forms are incorporated into polypeptides by living organisms through a process known as protein synthesis. Each L-α-amino acid has unique properties determined by its side chain (R-group), which influences its solubility, acidity, basicity, and reactivity.
Common applications of L-α-amino acids include pharmaceuticals, food additives, nutritional supplements, and as building blocks in the development of synthetic peptides. Their high purity and well-defined structure make them essential components in various biochemical research and industrial processes.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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beta-N-Methylamino-L-alanine | 741643-07-2 | C4H10N2O2 |
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Nicotianamine | 34441-14-0 | C12H21N3O6 |
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L-Methionine Sulfoxide | 3226-65-1 | C5H11NO3S |
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(2S,3S)-2,3-diaminobutanoic acid | 80999-51-5 | C4H10N2O2 |
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L-Threonine, 4-fluoro- | 89426-34-6 | C4H8FNO3 |
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(s)-2-Amino-3-cyclopropylpropanoic acid | 102735-53-5 | C6H11NO2 |
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Butanoic acid,2-amino-4-[(R)-methylsulfinyl]-, (2S)-rel- | 121249-48-7 | C5H11NO3S |
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Oxfenicine | 32462-30-9 | C8H9NO3 |
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L-Thioproline | 34592-47-7 | C4H7NO2S |
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L-Norvaline | 6600-40-4 | C5H11NO2 |
Related Literature
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Dan Yang,Yanping Zhou,Xianhong Rui,Jixin Zhu,Ziyang Lu,Eileen Fong,Qingyu Yan RSC Adv., 2013,3, 14960-14962
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Tao Wang,Yangyang Liu,Yue Deng,Hongbo Fu,Jianmin Chen Environ. Sci.: Nano, 2018,5, 1821-1833
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Jing Yu,Yu-Qi Lyu,Jiapeng Liu,Mohammed B. Effat,Junxiong Wu J. Mater. Chem. A, 2019,7, 17995-18002
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Yu Long,Bing Yuan,Jianrui Niu,Xin Tong,Jiantai Ma New J. Chem., 2015,39, 1179-1185
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Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
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