Bipyrimidines and oligopyrimidines
Bipyrimidines and oligopyrimidines represent a class of heterocyclic compounds that are characterized by the presence of multiple pyrimidine rings. Bipyrimidines typically consist of two pyrimidine units linked through nitrogen or carbon atoms, while oligopyrimidines encompass a broader category with three or more pyrimidine rings in a linear or cyclic arrangement.
These molecules exhibit diverse applications due to their unique structural features and electronic properties. In the pharmaceutical industry, bipyrimidines and oligopyrimidines are of interest for their potential as antiviral agents, particularly against RNA viruses such as HIV and hepatitis C. They also show promise in anti-inflammatory research, acting as potent inhibitors of various enzymes involved in inflammatory pathways.
Additionally, these compounds find utility in the development of organic electronics, where their electronic conductivity can be fine-tuned by varying the number and arrangement of pyrimidine units. The synthetic versatility of bipyrimidines and oligopyrimidines allows for the creation of derivatives with tailored properties, making them valuable tools in both academic research and industrial applications.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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2,2'-Bipyrimidine | 34671-83-5 | C8H6N4 |
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HYDROXY DESMETHYL BOSENTAN | 253688-62-9 | C26H27N5O7S |
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Hydroxy Bosentan-d6 | 1246817-57-1 | C27H29N5O7S |
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4-(2-Hydroxy-1,1-dimethylethyl)-N-6-chloro-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-ylbenzenesulfonamide | 1076198-22-5 | C25H24ClN5O5S |
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1342846-66-5 | C9H6N4O | |
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5-(7-Methyl-4-morpholino-6-(piperazin-1-ylmethyl)thieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine | 1032756-62-9 | C20H26N8OS |
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5-(5-Methyl-4-morpholinothieno[2,3-d]pyrimidin-2-yl)pyrimidin-2-amine | 1033740-44-1 | C15H16N6OS |
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4-Chloro-6-2-(1,1-dimethylethoxy)ethoxy-5-(2-methoxyphenoxy)-2,2'-bipyrimidine | 1177447-87-8 | C21H23ClN4O4 |
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N-[6-(benzyloxy)pyrimidin-4-yl]pyrimidine-2-carboxamide | 1396857-73-0 | C16H13N5O2 |
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Bosentan-d4 | 1065472-77-6 | C27H29N5O6S |
Related Literature
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Alvin Tanudjaja,Shinsuke Inagi,Fusao Kitamura,Toshikazu Takata,Ikuyoshi Tomita Dalton Trans., 2021,50, 3037-3043
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Li-Hua Gan,Rui Wu,Jian-Lei Tian,Patrick W. Fowler Phys. Chem. Chem. Phys., 2017,19, 419-425
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Kanjun Sun,Fengting Hua,Shuzhen Cui,Yanrong Zhu,Hui Peng,Guofu Ma RSC Adv., 2021,11, 37631-37642
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Adeline Huiling Loo,Alessandra Bonanni,Martin Pumera Analyst, 2013,138, 467-471
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Priyambada Nayak,Tanmaya Badapanda,Anil Kumar Singh,Simanchalo Panigrahi RSC Adv., 2017,7, 16319-16331
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