Benzenesulfonamides
Benzenesulfonamides are a class of organic compounds characterized by the presence of a sulfonamide group (-SO?NH?) attached to a benzene ring. These derivatives find extensive applications in various fields due to their unique chemical properties and functional groups. Commonly, benzenesulfonamides exhibit excellent solubility in polar solvents, making them suitable for pharmaceuticals, pesticides, and dye manufacturing.
In the pharmaceutical industry, benzenesulfonamides are frequently used as intermediates or active pharmaceutical ingredients (APIs). Their ability to form stable salts with acids makes them ideal for the formulation of tablets, capsules, and other dosage forms. Additionally, their inherent acidity can be leveraged in pH-sensitive drug delivery systems.
In agriculture, these compounds often serve as key components in herbicides and fungicides due to their broad-spectrum activity against plant pathogens. The sulfonamide group provides strong binding affinity to target sites, enhancing the efficacy of these products.
Overall, benzenesulfonamides represent a versatile class of molecules with diverse applications across multiple industries, driven by their chemical stability and reactivity.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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4-chloro-N-ethyl-2-nitrobenzene-1-sulfonamide | 89840-87-9 | C8H9ClN2O4S |
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(5-bromo-2-methyl-1-(phenylsulfonyl)-1H-indol-3-yl)methanol | 919295-68-4 | C16H14BrNO3S |
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Benzenesulfonamide, 3-(1-aminoethyl)-N-(1,1-dimethylethyl)- | 918810-68-1 | C12H20N2O2S |
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1,3-Benzenedisulfonamide, 5-(aminomethyl)- | 918810-53-4 | C7H11N3O4S2 |
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N-Benzyl 5-borono-2-methoxybenzenesulfonamide | 874219-51-9 | C14H16BNO5S |
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N- Butylbenzenesulfonamide | 3622-84-2 | C10H15NO2S |
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4-Hydroxytolbutamide | 5719-85-7 | C12H18N2O4S |
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Valdecoxib | 181695-72-7 | C16H14N2O3S |
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1-(2-Mesitylenesulfonyl)-3-nitro-1H-1,2,4-triazole | 74257-00-4 | C11H12N4O4S |
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Daltroban | 79094-20-5 | C16H16ClNO4S |
Related Literature
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Piotr Szcze?niak,Sebastian Stecko RSC Adv., 2015,5, 30882-30888
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Adeline Huiling Loo,Alessandra Bonanni,Martin Pumera Analyst, 2013,138, 467-471
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James D. Kirkham,Patrick M. Delaney,George J. Ellames,Eleanor C. Row,Joseph P. A. Harrity Chem. Commun., 2010,46, 5154-5156
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Li-Hua Gan,Rui Wu,Jian-Lei Tian,Patrick W. Fowler Phys. Chem. Chem. Phys., 2017,19, 419-425
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Priyambada Nayak,Tanmaya Badapanda,Anil Kumar Singh,Simanchalo Panigrahi RSC Adv., 2017,7, 16319-16331
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