Benzenesulfonamides
Benzenesulfonamides are a class of organic compounds characterized by the presence of a sulfonamide group (-SO?NH?) attached to a benzene ring. These derivatives find extensive applications in various fields due to their unique chemical properties and functional groups. Commonly, benzenesulfonamides exhibit excellent solubility in polar solvents, making them suitable for pharmaceuticals, pesticides, and dye manufacturing.
In the pharmaceutical industry, benzenesulfonamides are frequently used as intermediates or active pharmaceutical ingredients (APIs). Their ability to form stable salts with acids makes them ideal for the formulation of tablets, capsules, and other dosage forms. Additionally, their inherent acidity can be leveraged in pH-sensitive drug delivery systems.
In agriculture, these compounds often serve as key components in herbicides and fungicides due to their broad-spectrum activity against plant pathogens. The sulfonamide group provides strong binding affinity to target sites, enhancing the efficacy of these products.
Overall, benzenesulfonamides represent a versatile class of molecules with diverse applications across multiple industries, driven by their chemical stability and reactivity.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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Benzenesulfonic acid,4-(acetylamino)-, 2-[(3-nitrophenyl)methylene]hydrazide | 5448-82-8 | C15H14N4O5S |
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1-(4-bromophenyl)sulfonylazetidine | 530081-57-3 | C9H10BrNO2S |
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4-cyano-N,N-dimethylbenzene-1-sulfonamide | 63877-94-1 | C9H10N2O2S |
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1H-Imidazole, 2,4,5-tribromo-1-[(4-methylphenyl)sulfonyl]- | 6595-50-2 | C10H7Br3N2O2S |
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Benzenesulfonic acid,4-(acetylamino)-, 2-[1-(4-methylphenyl)ethylidene]hydrazide | 5448-96-4 | C17H19N3O3S |
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4-chloro-N-3-(dimethylamino)propyl-3-nitrobenzene-1-sulfonamide | 53803-81-9 | C11H16ClN3O4S |
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N-4-(dimethylsulfamoyl)phenylacetamide | 54951-54-1 | C10H14N2O3S |
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Benzenesulfohydroxamic Acid | 599-71-3 | C6H7NO3S |
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Benzamide,5-chloro-2-methoxy-N-[2-[4-[[[(methylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]- | 52994-25-9 | C18H20ClN3O5S |
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N4-Acetyl Sulfadoxine | 5018-54-2 | C14H16N4O5S |
Related Literature
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Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
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Jason Wan Lab Chip, 2020,20, 4528-4538
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Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
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Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932
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Bo Wei,Zhenyu Liu,Chen Xie,Shu Yang,Wentao Tang,Aiwei Gu,Wing-Tak Wong,Ka-Leung Wong J. Mater. Chem. C, 2015,3, 12322-12327
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