Production Method 1

32507-45-2

97985-66-5

Reaction Conditions

1.1 Reagents: Oxygen Catalysts: 2,2′-Dipyridyl disulfide Solvents: Acetone ;  18 h, rt

Reference

Regioselective Disulfide-Catalyzed Photocatalytic Oxidative Cleavage of 1-Arylbutadienes to Cinnamaldehydes

Fernandes, Rodney A. ; Kumar, Praveen; Bhowmik, Amit; Gorve, Dnyaneshwar A., Organic Letters, 2022, 24(19), 3435-3439

Production Method 2

32507-45-2

97985-66-5

Reaction Conditions

1.1 Reagents: Oxygen ,  Ferric sulfate hydrate Solvents: Acetonitrile ,  Water ;  rt → 45 °C; 21 h, 45 °C

Reference

Iron(III)/O2-Mediated Regioselective Oxidative Cleavage of 1-Arylbutadienes to Cinnamaldehydes

Bhowmik, Amit; Fernandes, Rodney A., Organic Letters, 2019, 21(22), 9203-9207

Production Method 3

86610-62-0

97985-66-5

Reaction Conditions

1.1 Reagents: Dipyridinium dichromate Solvents: Dichloromethane ;  24 h, 25 °C

Reference

Highly Enantioselective Synthesis of Functionalized Glutarimide Using Oxidative N-Heterocyclic Carbene Catalysis: A Formal Synthesis of (-)-Paroxetine

Porey, Arka; Santra, Surojit; Guin, Joyram, Journal of Organic Chemistry, 2019, 84(9), 5313-5327

Production Method 4

3132-99-8

97985-66-5

Reaction Conditions

1.1 Reagents: Sodium hydroxide Solvents: Water ;  25 °C; overnight, rt
1.2 Reagents: Acetic acid Solvents: Water ;  neutralized, rt

Reference

Production of myxopyronin and its derivatives by mutasynthesis employing a genetically modified myxopyronin genes

, World Intellectual Property Organization, , ,

Production Method 5

3132-99-8

97985-66-5

Reaction Conditions

1.1 Reagents: Sodium hydroxide Solvents: Methanol ,  Water ;  rt

Reference

Synthesis of N-Vinyl Cinnamaldehyde Nitrones through Atropisomeric Quinoxaline-Derived N,N,O-Ligand-Promoted Chan-Lam Reaction

Chen, Hao; Wei, Cui; Pang, Guang-Li; Liang, Cui; Mo, Dong-Liang ; et al, Organic Letters, 2022, 24(32), 6013-6017

Production Method 6

3132-99-8

1099-45-2

97985-66-5

Reaction Conditions

1.1 -
1.2 Reagents: Diisobutylaluminum hydride
1.3 Reagents: Manganese oxide (MnO2)

Reference

Secondary amine-catalyzed [3 + 3] benzannulation to access polysubstituted benzenes through iminium activation

Jiang, Lin; Li, Hang; Zhou, Jiang-Feng; Yuan, Ming-Wei; Li, Hong-Li; et al, Synthetic Communications, 2018, 48(3), 336-343

Production Method 7

3132-99-8

2136-75-6

97985-66-5

Reaction Conditions

1.1 Solvents: Toluene ;  50 °C

Reference

Synergistic catalysis: cis-cyclopropanation of benzoxazoles

Meazza, Marta; Light, Mark E.; Mazzanti, Andrea; Rios, Ramon, Chemical Science, 2016, 7(2), 984-988

Production Method 8

97985-66-5

Reaction Conditions

Reference

One-Pot, Four-Step Organocatalytic Asymmetric Synthesis of Functionalized Nitrocyclopropanes

Zaghi, Anna; Bernardi, Tatiana; Bertolasi, Valerio; Bortolini, Olga; Massi, Alessandro; et al, Journal of Organic Chemistry, 2015, 80(18), 9176-9184

Production Method 9

86610-62-0

97985-66-5

Reaction Conditions

1.1 Reagents: Manganese oxide (MnO2) Solvents: Hexane ,  Ethyl acetate ;  1 - 4 h, rt

Reference

Titanium-Catalyzed Intermolecular Hydroaminoalkylation of Conjugated Dienes

Preuss, Till; Saak, Wolfgang; Doye, Sven, Chemistry - A European Journal, 2013, 19(12), 3833-3837

Production Method 10

86610-62-0

97985-66-5

Reaction Conditions

1.1 Reagents: Dess-Martin periodinane Solvents: Dichloromethane ;  rt

Reference

Emission Wavelength Prediction of a Full-Color-Tunable Fluorescent Core Skeleton, 9-Aryl-1,2-dihydropyrrolo[3,4-b]indolizin-3-one

Kim, Eunha; Koh, Minseob; Lim, Byung Joon; Park, Seung Bum, Journal of the American Chemical Society, 2011, 133(17), 6642-6649

Production Method 11

210115-30-3

97985-66-5

Reaction Conditions

1.1 Reagents: p-Toluenesulfonic acid ,  Oxygen Catalysts: tert-Butyl nitrite ,  Bis(benzonitrile)dichloropalladium Solvents: tert-Butanol ,  Mesitylene ;  8 h, 1 atm, 25 °C
1.2 Solvents: Water ;  25 °C

Reference

Dehydrogenative Synthesis of Linear α,β-Unsaturated Aldehydes with Oxygen at Room Temperature Enabled by tBuONO

Wang, Mei-Mei; Ning, Xiao-Shan; Qu, Jian-Ping; Kang, Yan-Biao, ACS Catalysis, 2017, 7(6), 4000-4003

Production Method 12

210115-30-3

97985-66-5

Reaction Conditions

1.1 Reagents: Tempo Catalysts: 1,10-Phenanthroline ,  Iron chloride (FeCl3) Solvents: Chlorobenzene ;  12 h, 120 °C

Reference

Iron-Catalyzed α,β-Dehydrogenation of Carbonyl Compounds

Zhang, Xiao-Wei; Jiang, Guo-Qing; Lei, Shu-Hui; Shan, Xiang-Huan; Qu, Jian-Ping ; et al, Organic Letters, 2021, 23(5), 1611-1615

Production Method 13

3132-99-8

2136-75-6

97985-66-5

Reaction Conditions

1.1 Solvents: Toluene ;  overnight, 80 °C

Reference

Potent inhibition of nicotinamide N-methyltransferase by alkene-linked bisubstrate mimics bearing electron deficient aromatics

Gao, Yongzhi; van Haren, Matthijs J. ; Buijs, Ned; Innocenti, Paolo; Zhang, Yurui; et al, Journal of Medicinal Chemistry, 2021, 64(17), 12938-12963

Production Method 14

3132-99-8

97985-66-5

Reaction Conditions

1.1 Reagents: Cesium carbonate Catalysts: Copper oxide (CuO) (supported on magnesium exchanged zeolite-Y) Solvents: Ethanol ;  10 h, 100 °C

Reference

Dehydrogenation of ethanol over CuO-Mg-Y for cross-aldol condensation with aryl aldehydes

Biswas, Subir; Baruah, Manash J.; Gogoi, Gautam; Hoque, Nazimul; Lee, Seonghwan; et al, Microporous and Mesoporous Materials, 2022, 336,

Production Method 15

3132-99-8

2136-75-6

97985-66-5

Reaction Conditions

1.1 Solvents: Tetrahydrofuran ;  16 h, 70 °C

Reference

Enantioselective conjugate addition of malonates to α,β-unsaturated aldehydes catalysed by 4-oxalocrotonate tautomerase

Yu, Ming-Zhu; Chen, Kai-Yue; Zhang, Yi-Bin; Zhang, Chang-Xuan; Xiang, Zheng, Organic & Biomolecular Chemistry, 2023, 21(10), 2086-2090

Production Method 16

3132-99-8

62942-43-2

97985-66-5

Reaction Conditions

1.1 Reagents: Triethylamine Solvents: Dichloromethane ;  rt; 92 h, rt

Reference

Visible-light excitation of iminium ions enables the enantioselective catalytic β-alkylation of enals

Silvi, Mattia; Verrier, Charlie; Rey, Yannick P.; Buzzetti, Luca; Melchiorre, Paolo, Nature Chemistry, 2017, 9(9), 868-873

Production Method 17

3132-99-8

97985-66-5

Reaction Conditions

1.1 Reagents: 1,1,1,3,3,3-Hexafluoro-2-propanol ,  Water Solvents: Acetonitrile ;  rt

Reference

Electrochemical Formation of Cinnamaldehyde by the Electrolyte System N,N-Diisopropylethylamine and 1,1,1,3,3,3-Hexafluoropropan-2-ol

Imada, Yasushi; Okada, Yohei; Chiba, Kazuhiro, ChemElectroChem, 2020, 7(7), 1619-1622

Production Method 18

3132-99-8

97985-66-5

Reaction Conditions

1.1 Reagents: Sodium hydroxide Solvents: Water ;  25 °C; overnight, 25 °C
1.2 Reagents: Acetic acid ;  neutralized

Reference

Advanced Mutasynthesis Studies on the Natural α-Pyrone Antibiotic Myxopyronin from Myxococcus fulvus

Sahner, J. Henning; Sucipto, Hilda; Wenzel, Silke C.; Groh, Matthias; Hartmann, Rolf W.; et al, ChemBioChem, 2015, 16(6), 946-953

Production Method 19

3132-99-8

2136-75-6

97985-66-5

Reaction Conditions

1.1 Solvents: Dichloromethane ;  rt

Reference

Palladium-Catalyzed [5 + 2] Annulation of Vinylethylene Carbonates with Barbiturate-Derived Alkenes

Gao, Xing ; Zhu, Dongyu; Chen, Yuehua; Deng, Hao; Jiang, Feng; et al, Organic Letters, 2020, 22(18), 7158-7163

Production Method 20

141-82-2

3132-99-8

97985-66-5

Reaction Conditions

1.1 Reagents: Piperidine Solvents: Acetic acid ;  rt; 2.5 min
1.2 Reagents: Triethylamine ,  Ethyl chloroformate Solvents: Tetrahydrofuran ;  -7 °C; 1 h, -7 °C; -7 °C → rt
1.3 Reagents: Methanol ,  Sodium borohydride ;  0 °C; 12 h, 25 °C
1.4 Reagents: Pyridinium chlorochromate Solvents: Dichloromethane ;  12 h, 25 °C

Reference

De novo synthesis of functionalized 1,3-enynes and extended conjugated molecular systems

Rao, Maddali L. N.; Dasgupta, Priyabrata; Murty, Venneti N., RSC Advances, 2015, 5(32), 24834-24845

3-(3-bromophenyl)prop-2-enal Raw materials

• propanedioic acid
• 3-(3-bromophenyl)prop-2-en-1-ol
• 3-Bromobenzaldehyde
• (Formylmethyl)triphenylphosphonium chloride
• (Triphenylphosphoranylidene)acetaldehyde
• ethyl 2-(triphenyl-λ?-phosphanylidene)acetate
• 3-(3-Bromophenyl)propanal
• Benzene, 1-bromo-3-(1,3-butadienyl)-, (E)-

3-(3-bromophenyl)prop-2-enal Preparation Products

• 3-(3-bromophenyl)prop-2-enal (97985-66-5)

• 1. Fast synthesis of copper nanoclusters through the use of hydrogen peroxide additive and their application for the fluorescence detection of Hg2+ in water samples?
  Liao Xiaoqing,Li Ruiyi,Li Zaijun,Sun Xiulan,Wang Zhouping,Liu Junkang New J. Chem., 2015,39, 5240-5248
• 2. Fe(ii)-Assisted one-pot synthesis of ultra-small core–shell Au–Pt nanoparticles as superior catalysts towards the HER and ORR?
  Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466
• 3. Emulsifier-free, organotellurium-mediated living radical emulsion polymerization (emulsion TERP) of styrene: poly(dimethylaminoethyl methacrylate) macro-TERP agent?
  Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792
• 4. Fe/Fe3C@C nanoparticles encapsulated in N-doped graphene–CNTs framework as an efficient bifunctional oxygen electrocatalyst for robust rechargeable Zn–air batteries?
  Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
• 5. Establishing plasmon contribution to chemical reactions: alkoxyamines as a thermal probe?
  Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161

• 138555-58-5(3-(2-bromophenyl)prop-2-enal)
• 105330-15-2(3-(3,4-dibromophenyl)prop-2-enal)
• 26891-02-1(3-Buten-2-one, 4-(3-bromophenyl)-)
• 49678-05-9((2E,4E)-5-(4-Bromophenyl)-2,4-pentadienal)
• 3893-18-3(4-Bromocinnamaldehyde)
• 15185-59-8(3-(3-Bromophenyl)acrylaldehyde)
• 23958-26-1(Benzene, 1,1'-(1E)-1,2-ethenediylbis[3-bromo-)
• 49678-04-8(4-Bromocinnamaldehyde)
• 65300-30-3((3E)-4-(3-Bromophenyl)but-3-en-2-one)
• 105330-16-3(2,4-Pentadienal, 5-(3,4-dibromophenyl)-)