- Preparation of tricyclic fused nitrogen-containing heterocyclic compounds as selective histamine 4 receptor (H4 R)antagonists, World Intellectual Property Organization, , ,
Cas no 97941-89-4 (5,6-Dichloropyridine-2,3-diamine)
97941-89-4 structure
Product Name:5,6-Dichloropyridine-2,3-diamine
CAS No:97941-89-4
MF:C5H5Cl2N3
MW:178.019298315048
CID:1026430
PubChem ID:13492641
Update Time:2024-10-25
5,6-Dichloropyridine-2,3-diamine Chemical and Physical Properties
Names and Identifiers
-
- 5,6-Dichloropyridine-2,3-diamine
- 5,6-dichloro-2,3-Pyridinediamine
- 2,3-Diamino-5,6-dichloropyridine
- 2,3-Pyridinediamine,5,6-dichloro
- 5,6-dichloro-pyridine-2,3-diyldiamine
- 5,6-Dichlor-pyridin-2,3-diyldiamin
- 2,3-Pyridinediamine, 5,6-dichloro-
- CHGCWQGIACIHHI-UHFFFAOYSA-N
- 5,6-dichloropyridin-2,3-diamine
- 5,6-dichloro-pyridine-2,3-diamine
- 6845AC
- NE38205
- 5,6-Dichloro-2,3-pyridinediamine (ACI)
- Pyridine, 2,3-diamino-5,6-dichloro- (6CI)
- DS-14683
- DB-082927
- AKOS016005875
- MFCD13181782
- SCHEMBL8479600
- O11323
- 97941-89-4
- EN300-122195
- CS-0187084
- DTXSID70542129
-
- MDL： MFCD13181782
- Inchi： 1S/C5H5Cl2N3/c6-2-1-3(8)5(9)10-4(2)7/h1H,8H2,(H2,9,10)
- InChI Key： CHGCWQGIACIHHI-UHFFFAOYSA-N
- SMILES： ClC1C(Cl)=CC(N)=C(N)N=1
Computed Properties
- Exact Mass: 176.98600
- Monoisotopic Mass: 176.9860526g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 10
- Rotatable Bond Count: 0
- Complexity: 122
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 64.9
- XLogP3: 1.4
Experimental Properties
- Density: 1.602±0.06 g/cm3 (20 oC 760 Torr),
- Melting Point: 167 oC (water )
- Solubility: Slightly soluble (1.3 g/l) (25 o C),
- PSA: 64.93000
- LogP: 2.71520
5,6-Dichloropyridine-2,3-diamine Customs Data
- HS CODE：2933399090
- Customs Data：
China Customs Code:
2933399090Overview:
2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
5,6-Dichloropyridine-2,3-diamine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | CO894-5g |
5,6-Dichloropyridine-2,3-diamine |
97941-89-4 | 95+% | 5g |
9996CNY | 2021-05-07 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | CO894-1g |
5,6-Dichloropyridine-2,3-diamine |
97941-89-4 | 95+% | 1g |
3598CNY | 2021-05-07 | |
| Fluorochem | 231010-250mg |
5,6-Dichloropyridine-2,3-diamine |
97941-89-4 | 95% | 250mg |
￡145.00 | 2022-02-28 | |
| Fluorochem | 231010-1g |
5,6-Dichloropyridine-2,3-diamine |
97941-89-4 | 95% | 1g |
￡290.00 | 2022-02-28 | |
| Fluorochem | 231010-5g |
5,6-Dichloropyridine-2,3-diamine |
97941-89-4 | 95% | 5g |
￡790.00 | 2022-02-28 | |
| TRC | D476123-10mg |
5,6-dichloropyridine-2,3-diamine |
97941-89-4 | 10mg |
$ 50.00 | 2022-06-05 | ||
| TRC | D476123-50mg |
5,6-dichloropyridine-2,3-diamine |
97941-89-4 | 50mg |
$ 185.00 | 2022-06-05 | ||
| TRC | D476123-100mg |
5,6-dichloropyridine-2,3-diamine |
97941-89-4 | 100mg |
$ 275.00 | 2022-06-05 | ||
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | D899971-1g |
5,6-Dichloropyridine-2,3-diamine |
97941-89-4 | ≥95% | 1g |
2,923.20 | 2021-05-17 | |
| Chemenu | CM132583-250mg |
5,6-dichloropyridine-2,3-diamine |
97941-89-4 | 95% | 250mg |
$*** | 2023-04-20 |
5,6-Dichloropyridine-2,3-diamine Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Hydrochloric acid , Stannous chloride Solvents: Water ; 0.5 h, 80 - 100 °C
1.2 Reagents: Sodium hydroxide Solvents: Water ; pH 7
1.2 Reagents: Sodium hydroxide Solvents: Water ; pH 7
Reference
Production Method 2
Reaction Conditions
1.1 Reagents: Iron , Water , Ammonium chloride Solvents: Ethanol ; 3 h, 60 °C
Reference
- Preparation of hetero ring-fused imidazole derivatives as AMPK activators, World Intellectual Property Organization, , ,
Production Method 3
Reaction Conditions
1.1 Reagents: Iron , Ammonium chloride Solvents: Ethanol , Water ; 3 h, 60 °C
Reference
- Azabenzimidazole derivatives having AMPK-activating activity, World Intellectual Property Organization, , ,
Production Method 4
Reaction Conditions
1.1 Reagents: Hydrochloric acid , Stannous chloride Solvents: Water ; 0.5 h, 100 °C
1.2 Reagents: Sodium hydroxide Solvents: Water ; pH 7, 100 °C
1.2 Reagents: Sodium hydroxide Solvents: Water ; pH 7, 100 °C
Reference
- Discovery of a Novel Highly Selective Histamine H4 Receptor Antagonist for the Treatment of Atopic DermatitisKo, Kwangseok; Kim, Hye-Jung; Ho, Pil-Su; Lee, Soon Ok; Lee, Ji-Eun; et al, Journal of Medicinal Chemistry, 2018, 61(7), 2949-2961
Production Method 5
Reaction Conditions
Reference
- 2,3-Dihydro-6,7-dichloro-pyrido[2,3-b]pyrazine-8-oxide as selective glycine antagonist with in vivo activityMicheli, Fabrizio; Cugola, Alfredo; Donati, Daniele; Missio, Andrea; Pecunioso, Angelo; et al, Bioorganic & Medicinal Chemistry, 1997, 5(12), 2129-2132
Production Method 6
Reaction Conditions
Reference
- Preparation of 8-aza-, 6-aza- and 6,8-diaza-1,4-dihydroquinoxaline-2,3-diones as antagonists for the glycine/NMDA receptor, United States, , ,
Production Method 7
Reaction Conditions
Reference
- 3-[(3'-Hydroxymethyl)-4'-hydroxybutyl]imidazo[4,5-b]pyridines - novel antiviral agentsCundy, Darren J.; Holan, George; Otaegui, Michelle; Simpson, Gregory W., Bioorganic & Medicinal Chemistry Letters, 1997, 7(6), 669-674
5,6-Dichloropyridine-2,3-diamine Raw materials
5,6-Dichloropyridine-2,3-diamine Preparation Products
5,6-Dichloropyridine-2,3-diamine Related Literature
-
Robert J. Meagher,Anson V. Hatch,Ronald F. Renzi,Anup K. Singh Lab Chip, 2008,8, 2046-2053
-
M. T. Colomer,S. Díaz-Moreno,A. Tamayo,A. L. Ortiz J. Mater. Chem. C, 2018,6, 12643-12651
-
Quan Xiang,Yiqin Chen,Zhiqin Li,Kaixi Bi,Guanhua Zhang,Huigao Duan Nanoscale, 2016,8, 19541-19550
-
Xiaofeng Lin RSC Adv., 2016,6, 9002-9006
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