Production Method 1

84476-99-3

960371-08-8

Reaction Conditions

1.1 Reagents: Lithium diisopropylamide Solvents: Tetrahydrofuran ;  -78 °C; -78 °C → rt; 2 h, rt
1.2 Reagents: Ammonium chloride Solvents: Water

Reference

Preparation of pyridopyrimidine derivatives and related compounds for treating spinal muscular atrophy

, World Intellectual Property Organization, , ,

Production Method 2

84476-99-3

960371-08-8

Reaction Conditions

1.1 Reagents: Lithium diisopropylamide Solvents: Tetrahydrofuran ;  rt → -78 °C; 15 min, -78 °C
1.2 Solvents: Tetrahydrofuran ;  30 min, -78 °C; -78 °C → 0 °C; 1 h, 0 °C
1.3 Reagents: Ammonium chloride Solvents: Water

Reference

Benzamide derivatives useful in the treatment of hydroxysteroid dehydrogenase-mediated diseases and their preparation

, World Intellectual Property Organization, , ,

2-(5-fluoro-2-pyridyl)acetonitrile Raw materials

• 2,5-Difluoropyridine

2-(5-fluoro-2-pyridyl)acetonitrile Preparation Products

• 2-(5-fluoro-2-pyridyl)acetonitrile (960371-08-8)

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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridines and derivatives
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives

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• 149488-78-8(2-(3-Fluoropyridin-2-yl)acetonitrile)
• 1841081-69-3(2,2-Bis(5-fluoropyridin-2-yl)acetonitrile)
• 1000504-35-7(2-(4-Fluoropyridin-2-yl)acetonitrile)
• 1000550-26-4((3-Fluoro-6-methylpyridin-2-yl)acetonitrile)
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