- Design and Synthesis of Novel Diaminoquinazolines with in Vivo Efficacy for β-Catenin/T-Cell Transcriptional Factor 4 Pathway InhibitionDehnhardt, Christoph M.; Venkatesan, Aranapakam M.; Chen, Zecheng; Ayral-Kaloustian, Semiramis; Dos Santos, Osvaldo; et al, Journal of Medicinal Chemistry, 2010, 53(2), 897-910
Cas no 959236-72-7 (7-iodo-1,2,3,4-tetrahydroquinazoline-2,4-dione)
959236-72-7 structure
Product Name:7-iodo-1,2,3,4-tetrahydroquinazoline-2,4-dione
CAS No:959236-72-7
MF:C8H5IN2O2
MW:288.041973829269
MDL:MFCD09954830
CID:1025664
PubChem ID:34176106
Update Time:2024-10-25
7-iodo-1,2,3,4-tetrahydroquinazoline-2,4-dione Chemical and Physical Properties
Names and Identifiers
-
- 7-Iodoquinazoline-2,4(1H,3H)-dione
- 7-iodo-1H-quinazoline-2,4-dione
- 7-Iodoquizoline-2,4(1H,3H)-dione
- 2,4(1H,3H)-Quinazolinedione, 7-iodo-
- USQDOSUQXJGECF-UHFFFAOYSA-N
- 6584AC
- FCH1396613
- 7-Iodo-2,4(1H,3H)-quinazolinedione
- AX8224614
- D121496
- 7-Iodo-2,4(1H,3H)-quinazolinedione (ACI)
- 7-iodo-1,2,3,4-tetrahydroquinazoline-2,4-dione
- DTXSID60652948
- AKOS016003629
- DS-17311
- SCHEMBL4174954
- 959236-72-7
- DB-296787
- MFCD09954830
- CS-0040089
- F21427
- 7-IODO-1,3-DIHYDROQUINAZOLINE-2,4-DIONE
- 7-Iodoquinazoline-24(1H3H)-dione
- 7-Iodoquinazoline-2 pound not4(1H pound not3H)-dione
-
- MDL： MFCD09954830
- Inchi： 1S/C8H5IN2O2/c9-4-1-2-5-6(3-4)10-8(13)11-7(5)12/h1-3H,(H2,10,11,12,13)
- InChI Key： USQDOSUQXJGECF-UHFFFAOYSA-N
- SMILES： O=C1NC2C(=CC=C(C=2)I)C(=O)N1
Computed Properties
- Exact Mass: 287.93957g/mol
- Monoisotopic Mass: 287.93957g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 13
- Rotatable Bond Count: 0
- Complexity: 257
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 0.8
- Topological Polar Surface Area: 58.2
7-iodo-1,2,3,4-tetrahydroquinazoline-2,4-dione Security Information
- Signal Word：Warning
- Hazard Statement： H315-H319-H335
- Warning Statement： P261-P305+P351+P338
- Storage Condition：Keep in dark place,Sealed in dry,2-8°C
7-iodo-1,2,3,4-tetrahydroquinazoline-2,4-dione Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-GO547-1g |
7-iodo-1,2,3,4-tetrahydroquinazoline-2,4-dione |
959236-72-7 | 96% | 1g |
1455.0CNY | 2021-07-10 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-GO547-5g |
7-iodo-1,2,3,4-tetrahydroquinazoline-2,4-dione |
959236-72-7 | 96% | 5g |
6961CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-GO547-250mg |
7-iodo-1,2,3,4-tetrahydroquinazoline-2,4-dione |
959236-72-7 | 96% | 250mg |
1084CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-GO547-100mg |
7-iodo-1,2,3,4-tetrahydroquinazoline-2,4-dione |
959236-72-7 | 96% | 100mg |
517CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-GO547-50mg |
7-iodo-1,2,3,4-tetrahydroquinazoline-2,4-dione |
959236-72-7 | 96% | 50mg |
130.0CNY | 2021-07-10 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-GO547-200mg |
7-iodo-1,2,3,4-tetrahydroquinazoline-2,4-dione |
959236-72-7 | 96% | 200mg |
367.0CNY | 2021-07-10 | |
| Chemenu | CM126593-1g |
7-iodoquinazoline-2,4(1H,3H)-dione |
959236-72-7 | 96% | 1g |
$247 | 2021-08-05 | |
| Chemenu | CM126593-5g |
7-iodoquinazoline-2,4(1H,3H)-dione |
959236-72-7 | 96% | 5g |
$661 | 2021-08-05 | |
| Chemenu | CM126593-10g |
7-iodoquinazoline-2,4(1H,3H)-dione |
959236-72-7 | 96% | 10g |
$884 | 2021-08-05 | |
| Chemenu | CM126593-250mg |
7-iodoquinazoline-2,4(1H,3H)-dione |
959236-72-7 | 96% | 250mg |
$*** | 2023-03-29 |
7-iodo-1,2,3,4-tetrahydroquinazoline-2,4-dione Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Hydrochloric acid Solvents: Ethanol , Water ; overnight, 80 °C; 80 °C → 20 °C
Reference
Production Method 2
Reaction Conditions
1.1 Reagents: Hydrochloric acid Solvents: Ethanol , Water ; overnight, 80 °C; 80 °C → rt
Reference
- Amino-substituted quinazoline derivatives as inhibitors of β-cantenin/Tcf-4 pathway and cancer treatment agents and their preparation, World Intellectual Property Organization, , ,
7-iodo-1,2,3,4-tetrahydroquinazoline-2,4-dione Raw materials
7-iodo-1,2,3,4-tetrahydroquinazoline-2,4-dione Preparation Products
7-iodo-1,2,3,4-tetrahydroquinazoline-2,4-dione Related Literature
-
Luis Miguel Azofra,Douglas R. MacFarlane,Chenghua Sun Chem. Commun., 2016,52, 3548-3551
-
J. M. Granadino-Roldán,M. Fernández-Gómez,A. Navarro,T. Pe?a Ruiz,U. A. Jayasooriya Phys. Chem. Chem. Phys., 2004,6, 1133-1143
-
Bidyut Kumar Kundu,Rinky Singh,Ritudhwaj Tiwari,Debasis Nayak New J. Chem., 2019,43, 4867-4877
-
Haitao Li,Yu Pan,Zhizhi Wang,Shan Chen,Ruixin Guo,Jianqiu Chen RSC Adv., 2015,5, 100775-100782
959236-72-7 (7-iodo-1,2,3,4-tetrahydroquinazoline-2,4-dione) Related Products
- 86-96-4(Benzoyleneurea)
- 66868-15-3(2,4(1H,3H)-Quinazolinedione,sodium salt (1:1))
- 62484-20-2(2,4(1H,3H)-Quinazolinedione, 6,8-dimethyl-)
- 79689-45-5(2,4(1H,3H)-Quinazolinedione, 6-ethyl-)
- 67449-23-4(8-Methylquinazoline-2,4(1H,3H)-dione)
- 62484-16-6(6-methyl-1,2,3,4-tetrahydroquinazoline-2,4-dione)
- 16353-27-8(6-Iodo-1H-quinazoline-2,4-dione)
- 54243-58-2(6-Aminoquinazoline-2,4(1H,3H)-dione)
- 62484-15-5(7-methyl-1,2,3,4-tetrahydroquinazoline-2,4-dione)
- 33140-34-0(5-Iodoquinazoline-2,4-diol)
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