Production Method 1

58534-95-5

958458-89-4

Reaction Conditions

1.1 Reagents: Sodium nitrite ,  Hydrochloric acid Solvents: Acetonitrile ,  Water ;  30 min, 0 °C; 30 min, 0 °C
1.2 Reagents: Potassium iodide Solvents: Water ;  20 min, 0 °C; 0 °C → rt; 16 h, rt
1.3 Reagents: Sodium sulfite Solvents: Dichloromethane ;  10 min, rt

Reference

Synthesis of chryseno[1,2-b]heteroarenes and phenanthro[1,2-b:8,7-b']diheteroarenes by an SNAr-anionic cyclization cascade reaction strategy

Gilmore, James; Hwang, Daeseong; Crissy, Jack M. ; Mercado-Rodriguez, James M.; Katz, Jeffrey L., Tetrahedron Letters, 2020, 61(52),

Production Method 2

1072-85-1

958458-89-4

Reaction Conditions

1.1 Reagents: Butyllithium ,  2,2,6,6-Tetramethylpiperidine Solvents: Tetrahydrofuran ;  30 min, -78 °C
1.2 Solvents: Tetrahydrofuran ;  30 min, -78 °C
1.3 Reagents: Iodine

Reference

Fluorine-programmed nanozipping to tailored nanographenes on rutile TiO2 surfaces

Kolmer, M. ; Zuzak, R. ; Steiner, A. K. ; Zajac, L. ; Engelund, M. ; et al, Science (Washington, 2019, 363(6422), 57-60

Production Method 3

29632-73-3

958458-89-4

348-52-7

Reaction Conditions

1.1 Reagents: Sodium nitrite ,  Sodium tetrafluoroborate Solvents: Water
1.2 Reagents: Sulfuric acid ;  150 - 170 °C

Reference

Synthesis and biological activity studies of di- and mono-halo fluoro benzenes

Logoglu, Elif; Katircioglu, Hikmet; Tilki, Tahir; Oktemer, Atilla, Asian Journal of Chemistry, 2007, 19(3), 2029-2035

1-Bromo-2-fluoro-3-iodobenzene Raw materials

• 2-Bromo-4-iodoaniline
• 3-Bromo-2-fluoroaniline
• 1-Bromo-2-fluorobenzene

1-Bromo-2-fluoro-3-iodobenzene Preparation Products

• 1-Fluoro-2-iodobenzene (348-52-7)
• 1-Bromo-2-fluoro-3-iodobenzene (958458-89-4)

• 1. Establishing plasmon contribution to chemical reactions: alkoxyamines as a thermal probe?
  Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
• 2. Evidence of CO2 molecule acting as an electron acceptor on a nanoporous metal–organic-framework MIL-53 or Cr3+(OH)(O2C–C6H4–CO2)?
  Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
• 3. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
  Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
• 4. Excitable dynamics in the bromate–sulfite–ferrocyanide reaction
  J. Zagora,M. Vosla?,L. Schreiberová,I. Schreiber Phys. Chem. Chem. Phys., 2002,4, 1284-1291
• 5. Enabling chloride salts for thermal energy storage: implications of salt purity?
  J. Matthew Kurley,Phillip W. Halstenberg,Abbey McAlister,Stephen Raiman,Richard T. Mayes RSC Adv., 2019,9, 25602-25608

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Halobenzenes Iodobenzenes

• 116272-41-4(4-Bromo-1-fluoro-2-iodobenzene)
• 811842-30-5(2-Bromo-1-fluoro-4-iodobenzene)
• 207989-04-6(1-bromo-2,3-difluoro-4-iodo-benzene)
• 105931-73-5(4-Bromo-2-fluoro-1-iodobenzene)
• 136434-77-0(1-Bromo-2-fluoro-4-iodobenzene)
• 145349-66-2(4-Bromo-2,5-difluoroiodobenzene)
• 147425-25-0(Benzene, 1-bromo-2,4,5-trifluoro-3-iodo-)
• 914636-91-2(1-Bromo-2,4-difluoro-5-iodobenzene)
• 679836-60-3(1,5-Dibromo-2,4-difluoro-3-iodobenzene)
• 881667-35-2(1,2-dibromo-3-fluoro-4-iodobenzene)