- Method for preparing oseltamivir and its isomer, World Intellectual Property Organization, , ,
Cas no 956267-10-0 (4-N-Desacetyl-5-N-acetyl Oseltamivir)
956267-10-0 structure
Product Name:4-N-Desacetyl-5-N-acetyl Oseltamivir
CAS No:956267-10-0
MF:C16H28N2O4
MW:312.404524803162
CID:1062050
Update Time:2025-09-23
4-N-Desacetyl-5-N-acetyl Oseltamivir Chemical and Physical Properties
Names and Identifiers
-
- 4-N-Desacetyl-5-N-acetyl Oseltamivir
- Oseltamivir Impurity G
- Ethyl (3R,4R,5S)-5-(acetylamino)-4-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate (ACI)
-
- Inchi： 1S/C16H28N2O4/c1-5-12(6-2)22-14-9-11(16(20)21-7-3)8-13(15(14)17)18-10(4)19/h9,12-15H,5-8,17H2,1-4H3,(H,18,19)/t13-,14+,15+/m0/s1
- InChI Key： SEYYJZMDDOOQNB-RRFJBIMHSA-N
- SMILES： O([C@@H]1C=C(C(=O)OCC)C[C@H](NC(=O)C)[C@H]1N)C(CC)CC
Computed Properties
- Exact Mass: 312.20500
Experimental Properties
- PSA: 90.65000
- LogP: 2.37660
4-N-Desacetyl-5-N-acetyl Oseltamivir Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | D288370-2mg |
4-N-Desacetyl-5-N-acetyl Oseltamivir |
956267-10-0 | 2mg |
$167.00 | 2023-05-18 | ||
| TRC | D288370-5mg |
4-N-Desacetyl-5-N-acetyl Oseltamivir |
956267-10-0 | 5mg |
$227.00 | 2023-05-18 | ||
| TRC | D288370-10mg |
4-N-Desacetyl-5-N-acetyl Oseltamivir |
956267-10-0 | 10mg |
$ 425.00 | 2023-09-08 | ||
| TRC | D288370-25mg |
4-N-Desacetyl-5-N-acetyl Oseltamivir |
956267-10-0 | 25mg |
$ 1039.00 | 2023-09-08 | ||
| TRC | D288370-50mg |
4-N-Desacetyl-5-N-acetyl Oseltamivir |
956267-10-0 | 50mg |
$ 1748.00 | 2023-09-08 | ||
| A2B Chem LLC | AW54103-25mg |
4-N-Desacetyl-5-N-acetyl Oseltamivir |
956267-10-0 | > 95% | 25mg |
$599.00 | 2024-07-18 |
4-N-Desacetyl-5-N-acetyl Oseltamivir Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Dimethylbarbituric acid Catalysts: Triphenylphosphine , Palladium diacetate Solvents: Ethanol ; 3 h, 35 °C
1.2 Reagents: Sodium carbonate Solvents: Water ; pH 8
1.2 Reagents: Sodium carbonate Solvents: Water ; pH 8
Reference
Production Method 2
Reaction Conditions
1.1 Reagents: Trifluoroacetic acid Solvents: Dichloromethane ; 0 - 5 °C; 16 h, 25 - 30 °C; 30 °C → 0 °C
1.2 Reagents: Sodium bicarbonate Solvents: Water ; basified
1.2 Reagents: Sodium bicarbonate Solvents: Water ; basified
Reference
- Synthesis and characterization of potential pharmacopeial impurities of oseltamivir: an antiviral drugPonduri, Rajasekhar; Kumar, Pramod; Vadali, Lakshmana Rao; Aelugu, Komaraiah; Matcha, Kishore, Asian Journal of Chemistry, 2018, 30(9), 2003-2007
Production Method 3
Reaction Conditions
Reference
- Preparation method of acetamido cyclohexenoate, China, , ,
Production Method 4
Reaction Conditions
Reference
- The first synthesis of [11C]oseltamivir: a tool for elucidating the relationship between Tamiflu and its adverse effects on the central nervous systemArai, Takuya; Konno, Fujiko; Ogawa, Masanao; Zhang, Ming-Rong; Suzuki, Kazutoshi, Journal of Labelled Compounds and Radiopharmaceuticals, 2009, 52(9), 350-354
4-N-Desacetyl-5-N-acetyl Oseltamivir Raw materials
- Oseltamivir Impurity 15
- 1-Cyclohexene-1-carboxylic acid, 5-(acetylamino)-4-[[(1,1-dimethylethoxy)carbonyl]amino]-3-(1-ethylpropoxy)-, ethyl ester, (3R,4R,5S)-
4-N-Desacetyl-5-N-acetyl Oseltamivir Preparation Products
4-N-Desacetyl-5-N-acetyl Oseltamivir Related Literature
-
Qiaoe Wang,Meiling Lian,Xiaowen Zhu,Xu Chen RSC Adv., 2021,11, 192-197
-
Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
-
3. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198
-
Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
-
Fereshteh Bayat Environ. Sci.: Nano, 2021,8, 367-389
956267-10-0 (4-N-Desacetyl-5-N-acetyl Oseltamivir) Related Products
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- 1093851-61-6(Oseltamivir-d3)
- 312904-18-0(Ethyl (3R,4R,5S)-4-acetamido-3-pentan-3-yloxy-5-(prop-2-enylamino)cyclohexene-1-carboxylate)
- 196618-13-0(Oseltamivir)
- 873925-58-7(1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-propoxy-,(3S,4S,5R)-)
- 873925-62-3(1-Cyclohexene-1-carboxylic acid,4-(acetylamino)-5-amino-3-(2-propenyloxy)-, (3S,4S,5R)-)
- 873925-82-7(1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-butoxy-,(3S,4S,5R)-)
- 1052063-37-2(3-Des(1-ethylpropoxy)-3-(1-methylpropoxy) Oseltamivir)
- 873925-79-2(1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-ethoxy-,(3S,4S,5R)-)
- 208720-71-2(Oseltamivir Acid Methyl Ester)
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