Production Method 1

956-48-9

Reaction Conditions

Reference

Mechanism of the Gibbs Reaction. 3. Indophenol Formation via Radical Electrophilic Aromatic Substitution (SREAr) on Phenols

Pallagi, Istvan; Toro, Andras; Farkas, Odon, Journal of Organic Chemistry, 1994, 59(22), 6543-57

Production Method 2

956-48-9

Reaction Conditions

Reference

The color reaction of phenols with Gibbs reagent. Properties of the colored product and optimum reaction conditions

Svobodova, D.; Krenek, P.; Fraenkl, M.; Gasparic, J., Mikrochimica Acta, 1978, 2(3-4), 197-211

2,6-Dichlorophenolindophenol (Technical Grade) Preparation Products

• 2,6-Dichlorophenolindophenol (Technical Grade) (956-48-9)

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• 4. An all-solid-state imprinted polymer-based potentiometric sensor for determination of bisphenol S?
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• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds Quinonimines P-quinonimines
• Solvents and Organic Chemicals Organic Compounds Hydrocarbons

Comprehensive Technical Overview of 2,6-Dichlorophenolindophenol (Technical Grade) (CAS No. 956-48-9)

2,6-Dichlorophenolindophenol, commonly abbreviated as DCPIP (CAS No. 956-48-9), is a redox dye widely utilized in biochemical and industrial applications. Its technical grade variant is particularly valued for its stability and reactivity in various analytical procedures. This compound serves as a critical indicator in vitamin C assays, antioxidant capacity tests, and electron transport chain studies, making it indispensable in research and quality control laboratories.

The molecular structure of 2,6-Dichlorophenolindophenol features two chlorine atoms attached to a phenolindophenol backbone, which confers its distinctive blue color in oxidized form. This property is leveraged in spectrophotometric analyses, where it acts as a visual or spectrophotometric endpoint marker. Recent trends highlight its growing use in food science for assessing ascorbic acid content in beverages and processed foods, aligning with consumer demand for nutrient transparency and functional food labeling.

In the context of sustainability and green chemistry, researchers are exploring DCPIP's role in bio-based redox systems. Its ability to mimic natural electron acceptors makes it a candidate for enzyme-coupled assays and biocatalytic processes. A frequently searched question—"How does 2,6-Dichlorophenolindophenol work in photosynthesis experiments?"—reflects its educational relevance in demonstrating light-dependent reactions in plant biology curricula.

The technical grade specification of 956-48-9 ensures cost-effectiveness for large-scale industrial applications while maintaining sufficient purity for non-pharmaceutical uses. Analytical methods such as HPLC and titrimetry routinely employ this compound due to its sharp colorimetric transition between oxidized (blue) and reduced (colorless) states. This characteristic has spurred innovations in microfluidic sensors and point-of-care diagnostics, addressing the need for rapid antioxidant testing in clinical settings.

Storage and handling recommendations for 2,6-Dichlorophenolindophenol emphasize protection from light degradation and moisture absorption, topics frequently queried in laboratory forums. Its compatibility with aqueous buffers and organic solvents expands its utility across diverse experimental conditions. As the nutraceutical industry grows, demand for precise vitamin quantification tools like DCPIP is projected to rise, reinforcing its commercial significance.

Emerging applications include battery research, where DCPIP analogs are studied as redox mediators for energy storage systems. This aligns with global interest in renewable energy solutions, another high-traffic search topic. The compound's structure-activity relationship continues to inspire computational chemistry studies aiming to design improved electrochemical indicators with enhanced sensitivity.

In summary, 2,6-Dichlorophenolindophenol (Technical Grade) (CAS 956-48-9) remains a versatile tool bridging fundamental research and applied science. Its enduring relevance stems from adaptable physicochemical properties that meet evolving needs in life sciences, material innovation, and environmental monitoring—all domains generating substantial online engagement among professionals and academics alike.

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