Production Method 1

10167-97-2

955376-51-9

Reaction Conditions

1.1 Solvents: Ethanol ,  Water ;  overnight, reflux

Reference

Preparation of heterocyclylaminopyrazine derivatives for use as CHK-1 inhibitors

, World Intellectual Property Organization, , ,

Production Method 2

10167-97-2

955376-51-9

Reaction Conditions

1.1 Reagents: Sodium bicarbonate Solvents: Methanol ,  Water ;  2 h, reflux

Reference

Preparation of 1-(cyclopent-2-en-1-yl)-3-(2-hydroxy-3-(arylsulfonyl)phenyl)urea derivatives as CXCR2 inhibitors

, World Intellectual Property Organization, , ,

Production Method 3

10167-97-2

955376-51-9

Reaction Conditions

1.1 Reagents: Sodium bicarbonate Solvents: Ethanol ,  Methanol ;  25 °C; 6 h, 80 °C
1.2 Reagents: Sodium carbonate Solvents: Water ;  pH 11

Reference

Preparation of dichlorophenyl benzoxazole compounds, compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding

, World Intellectual Property Organization, , ,

Production Method 4

10167-97-2

955376-51-9

Reaction Conditions

1.1 Reagents: Sodium bicarbonate Solvents: Methanol ,  Water ;  2 h, rt → reflux

Reference

Synthesis, Reduction Potentials, and Antitubercular Activity of Ring A/B Analogues of the Bioreductive Drug (6S)-2-Nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)

Thompson, Andrew M.; Blaser, Adrian; Anderson, Robert F.; Shinde, Sujata S.; Franzblau, Scott G.; et al, Journal of Medicinal Chemistry, 2009, 52(3), 637-645

Production Method 5

426825-75-4

955376-51-9

Reaction Conditions

1.1 Reagents: 1,10-Phenanthroline ,  Cesium carbonate ,  Cuprous iodide Solvents: Methanol ,  Toluene ;  overnight, 120 °C

Reference

Preparation of [5,6]heterocyclic compounds having ossification-promoting activity

, World Intellectual Property Organization, , ,

Production Method 6

10167-97-2

955376-51-9

Reaction Conditions

1.1 Reagents: Sodium bicarbonate Solvents: Water ;  rt

Reference

IRAK-4 inhibitors. Part III: A series of imidazo[1,2-a]pyridines

Buckley, George M.; Fosbeary, Richard; Fraser, Joanne L.; Gowers, Lewis; Higueruelo, Alicia P.; et al, Bioorganic & Medicinal Chemistry Letters, 2008, 18(12), 3656-3660

Production Method 7

10167-97-2

955376-51-9

Reaction Conditions

1.1 Reagents: Sodium bicarbonate Solvents: Ethanol ;  5 h, 80 °C

Reference

Preparation of multi-cyclic imidazopyridine compounds and related heterocycles as IRAK and FLT3 inhibitors useful alone or in pharmaceutical compositions in treatment of cancer and other diseases

, World Intellectual Property Organization, , ,

6-Methoxyimidazo1,2-apyridine Raw materials

• 5-methoxypyridin-2-amine
• 6-Iodoimidazo[1,2-a]pyridine

6-Methoxyimidazo1,2-apyridine Preparation Products

• 6-Methoxyimidazo1,2-apyridine (955376-51-9)

• 1. Establishing empirical design rules of nucleic acid templates for the synthesis of silver nanoclusters with tunable photoluminescence and functionalities towards targeted bioimaging applications?
  Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932
• 2. Examination of deposit in commercial diluted phosphoric acid
  Analyst, 1880,5, 146-147
• 3. Elusive 2-aminofuran Diels–Alder substrates for a straightforward synthesis of polysubstituted anilines?
  Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
• 4. Excimer–monomer switch: a reaction-based approach for selective detection of fluoride?
  Qiao Song,Angela Bamesberger,Lingyun Yang,Haley Houtwed,Haishi Cao Analyst, 2014,139, 3588-3592
• 5. Exceptional activity of sub-nm Pt clusters on CdS for photocatalytic hydrogen production: a combined experimental and first-principles study?
  Qiyuan Wu,Shangmin Xiong,Peichuan Shen,Shen Zhao,Alexander Orlov Catal. Sci. Technol., 2015,5, 2059-2064

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Imidazopyridines Imidazopyridines
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Imidazopyridines

• 69214-22-8(Imidazo[1,2-a]pyridin-8-ol)
• 100592-11-8(imidazo1,2-apyridin-8-ol hydrochloride)
• 183208-36-8(5-methoxy-1H-pyrrolo[2,3-b]pyridine)
• 342613-71-2(Imidazo1,2-apyridin-7-ol Methyl Ether)
• 896139-85-8(Imidazo[1,2-a]pyridin-7-ol)
• 99261-88-8(Pyrido[1,2-a]benzimidazole,7-methoxy-)
• 99261-89-9(8-methoxy-Pyrido[1,2-a]benzimidazole)
• 1036990-93-8(7-ethoxy-Imidazo[1,2-a]pyridine)
• 100592-04-9(8-methoxyimidazo[1,2-a]pyridine)
• 885275-62-7(Imidazo1,2-apyridin-6-ol)