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  Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
• 2. Excess electrons in lithium–ethylamine solutions—density, electrical conductivity and EPR studies
  Phys. Chem. Chem. Phys., 1999,1, 3561-3565
• 3. Emergence of microfluidic wearable technologies
  Joo Chuan Yeo,Kenry Lab Chip, 2016,16, 4082-4090
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  Max Attwood,Hiroki Akutsu,Lee Martin,Toby J. Blundell,Pierre Le Maguere,Scott S. Turner Dalton Trans., 2021,50, 11843-11851
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Diphenylmethanes

Benzhydrol-d5 (CAS No. 95450-78-5): A Comprehensive Guide to Its Properties and Applications

Benzhydrol-d5, also known as deuterated benzhydrol, is a specialized chemical compound with the CAS number 95450-78-5. This deuterium-labeled variant of benzhydrol is widely used in research, pharmaceuticals, and analytical chemistry due to its unique isotopic properties. The compound is particularly valuable in mass spectrometry and nuclear magnetic resonance (NMR) studies, where its deuterium atoms provide distinct spectral signatures.

The molecular formula of Benzhydrol-d5 is C13D5H5O, indicating that five hydrogen atoms in the benzhydrol structure have been replaced with deuterium. This modification enhances its utility in isotopic labeling experiments and metabolic studies. Researchers often use Benzhydrol-d5 as an internal standard in quantitative analysis, ensuring accurate measurements in complex biological matrices.

One of the most significant applications of Benzhydrol-d5 is in the field of drug development. Pharmaceutical companies leverage its isotopic properties to track the metabolism of new drug candidates. This is particularly relevant given the growing interest in personalized medicine and precision dosing, topics that are currently trending in scientific and medical communities. The ability to monitor drug pathways with high precision aligns with the broader push toward tailored therapeutics.

In addition to its role in drug development, Benzhydrol-d5 is also employed in environmental analysis. Scientists use it to study the degradation of organic pollutants and to trace the movement of chemicals in ecosystems. This application is especially pertinent amid rising concerns about environmental sustainability and chemical safety, which are hot topics in both academic and public discourse.

The synthesis of Benzhydrol-d5 involves advanced techniques in deuterium chemistry, ensuring high isotopic purity. This purity is critical for its use in sensitive analytical methods. The compound is typically supplied as a white crystalline solid, soluble in common organic solvents such as methanol and acetonitrile. Its stability under standard laboratory conditions makes it a reliable choice for long-term studies.

From a market perspective, the demand for Benzhydrol-d5 is driven by the expanding fields of pharmaceutical research and environmental science. As regulatory agencies worldwide tighten guidelines on drug safety and environmental impact, the need for precise analytical tools like Benzhydrol-d5 is expected to grow. This trend is reflected in the increasing number of publications and patents citing its use.

For researchers looking to purchase Benzhydrol-d5 (CAS No. 95450-78-5), it is essential to source the compound from reputable suppliers who can provide certificates of analysis and isotopic purity. Proper storage in a cool, dry environment is recommended to maintain its integrity over time. Handling should follow standard laboratory safety protocols, although the compound is not classified as hazardous under normal conditions.

In summary, Benzhydrol-d5 is a versatile and invaluable tool in modern scientific research. Its applications span from drug metabolism studies to environmental monitoring, making it a cornerstone in laboratories worldwide. As science continues to advance toward more precise and sustainable solutions, compounds like Benzhydrol-d5 will undoubtedly play a pivotal role.

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