- Discovery of a Selective Aurora A Kinase Inhibitor by Virtual ScreeningKilchmann, Falco; Marcaida, Maria J.; Kotak, Sachin; Schick, Thomas; Boss, Silvan D.; et al, Journal of Medicinal Chemistry, 2016, 59(15), 7188-7211
Cas no 954238-88-1 ((2-AMINO-5-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER)
954238-88-1 structure
Product Name:(2-AMINO-5-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER
CAS No:954238-88-1
MF:C11H15ClN2O2
MW:242.702001810074
MDL:MFCD09701245
CID:1985472
PubChem ID:84820093
Update Time:2024-10-25
(2-AMINO-5-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER Chemical and Physical Properties
Names and Identifiers
-
- (2-AMINO-5-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER
- 1,1-Dimethylethyl N-(2-amino-5-chlorophenyl)carbamate (ACI)
- tert-Butyl (2-amino-5-chlorophenyl)carbamate
- G54982
- EN300-1878549
- SB40236
- DB-257504
- SCHEMBL15550749
- tert-Butyl(2-amino-5-chlorophenyl)carbamate
- CS-0342932
- MFCD09701245
- tert-butyl N-(2-amino-5-chlorophenyl)carbamate
- 954238-88-1
-
- MDL： MFCD09701245
- Inchi： 1S/C11H15ClN2O2/c1-11(2,3)16-10(15)14-9-6-7(12)4-5-8(9)13/h4-6H,13H2,1-3H3,(H,14,15)
- InChI Key： NMAXYAHHCCNXNL-UHFFFAOYSA-N
- SMILES： O=C(NC1C(N)=CC=C(Cl)C=1)OC(C)(C)C
Computed Properties
- Exact Mass: 242.0822054g/mol
- Monoisotopic Mass: 242.0822054g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 16
- Rotatable Bond Count: 4
- Complexity: 253
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.3
- Topological Polar Surface Area: 64.4?2
(2-AMINO-5-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | A596348-10mg |
(2-Amino-5-chloro-phenyl)-carbamic Acid tert-Butyl Ester |
954238-88-1 | 10mg |
$ 50.00 | 2022-06-08 | ||
| TRC | A596348-50mg |
(2-Amino-5-chloro-phenyl)-carbamic Acid tert-Butyl Ester |
954238-88-1 | 50mg |
$ 160.00 | 2022-06-08 | ||
| TRC | A596348-100mg |
(2-Amino-5-chloro-phenyl)-carbamic Acid tert-Butyl Ester |
954238-88-1 | 100mg |
$ 250.00 | 2022-06-08 | ||
| Alichem | A019117354-1g |
tert-Butyl (2-amino-5-chlorophenyl)carbamate |
954238-88-1 | 95% | 1g |
$541.53 | 2023-08-31 | |
| JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd. | 20R0444-1g |
(2-Amino-5-chloro-phenyl)-carbamic acid tert-butyl ester |
954238-88-1 | 96% | 1g |
2527.17CNY | 2021-05-08 | |
| JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd. | 20R0444-5g |
(2-Amino-5-chloro-phenyl)-carbamic acid tert-butyl ester |
954238-88-1 | 96% | 5g |
8463.46CNY | 2021-05-08 | |
| JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd. | 20R0444-500mg |
(2-Amino-5-chloro-phenyl)-carbamic acid tert-butyl ester |
954238-88-1 | 96% | 500mg |
1679.12CNY | 2021-05-08 | |
| JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd. | 20R0444-250mg |
(2-Amino-5-chloro-phenyl)-carbamic acid tert-butyl ester |
954238-88-1 | 96% | 250mg |
1263.58CNY | 2021-05-08 | |
| abcr | AB534774-1 g |
tert-Butyl (2-amino-5-chlorophenyl)carbamate, 95%; . |
954238-88-1 | 95% | 1g |
€564.60 | 2023-07-10 | |
| JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd. | 20R0444-1g |
(2-Amino-5-chloro-phenyl)-carbamic acid tert-butyl ester |
954238-88-1 | 96% | 1g |
￥4984.05 | 2025-04-11 |
(2-AMINO-5-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Sodium bicarbonate , Sodium dithionite Solvents: 1,4-Dioxane , Water ; 40 min, 100 °C
Reference
Production Method 2
Reaction Conditions
1.1 Catalysts: Guanidine hydrochloride Solvents: Ethanol ; 5 - 20 min, 35 - 40 °C
Reference
- BF3·OEt2 Mediated metal-free one-pot sequential multiple annulation cascade (SMAC) synthesis of complex and diverse tetrahydroisoquinoline fused hybrid moleculesShinde, Anand H.; Vidyacharan, Shinde; Sharada, Duddu S., Organic & Biomolecular Chemistry, 2016, 14(12), 3207-3211
(2-AMINO-5-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER Raw materials
- Di-tert-butyl dicarbonate
- Carbamic acid, (5-chloro-2-nitrophenyl)-, 1,1-dimethylethyl ester
- 4-chlorobenzene-1,2-diamine
(2-AMINO-5-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER Preparation Products
(2-AMINO-5-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER Related Literature
-
Dhamodaran Manikandan,S. Amirthapandian,I. S. Zhidkov,A. I. Kukharenko,S. O. Cholakh,Ramaswamy Murugan Phys. Chem. Chem. Phys., 2018,20, 6500-6514
-
Stephen P. Fletcher,Richard B. C. Jagt,Ben L. Feringa Chem. Commun., 2007, 2578-2580
-
Inês S. Albuquerque,Hélia F. Jeremias,Miguel Chaves-Ferreira,Dijana Matak-Vinkovic,Omar Boutureira,Carlos C. Rom?o Chem. Commun., 2015,51, 3993-3996
-
P. K. Wawrzyniak,M. T. P. Beerepoot,H. J. M. de Groot,F. Buda Phys. Chem. Chem. Phys., 2011,13, 10270-10279
-
Alvin Tanudjaja,Shinsuke Inagi,Fusao Kitamura,Toshikazu Takata,Ikuyoshi Tomita Dalton Trans., 2021,50, 3037-3043
954238-88-1 ((2-AMINO-5-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER) Related Products
- 5347-26-2(Carbanilic acid,m-chloro-, ethylene ester (8CI))
- 25058-37-1(Carbanilic acid,m-chloro-, 2-methoxyethyl ester (8CI))
- 2239-92-1(Carbamic acid,N-(4-chlorophenyl)-, 1-methylethyl ester)
- 2150-28-9(Carbamic acid,(3,4-dichlorophenyl)-, 1-methylethyl ester (9CI))
- 101-21-3(Chlorpropham)
- 5330-63-2(tert-butyl (3-chlorophenyl)carbamate)
- 79759-26-5(Carbamic acid, [4-chloro-2-[(3-chlorophenyl)amino]phenyl]-, ethyl ester)
- 18437-66-6(Tert-Butyl 4-chlorophenylcarbamate)
- 58518-38-0(1-hydroxypropan-2-yl (3-chlorophenyl)carbamate)
- 954238-81-4((2-Amino-3-chloro-phenyl)-carbamic Acid tert-Butyl Ester)
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