Cas no 954238-73-4 ((2-AMINO-3-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER)
(2-AMINO-3-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER Chemical and Physical Properties
Names and Identifiers
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- (2-AMINO-3-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER
- CS-0371719
- DB-257499
- (2-Amino-3-bromo-phenyl)-carbamicacidtert-butylester
- TERT-BUTYL N-(2-AMINO-3-BROMOPHENYL)CARBAMATE
- SB40232
- tert-Butyl (2-amino-3-bromophenyl)carbamate
- 954238-73-4
-
- MDL: MFCD09701240
- Inchi: 1S/C11H15BrN2O2/c1-11(2,3)16-10(15)14-8-6-4-5-7(12)9(8)13/h4-6H,13H2,1-3H3,(H,14,15)
- InChI Key: IUKRRDXOAMPHGS-UHFFFAOYSA-N
- SMILES: BrC1=CC=CC(=C1N)NC(=O)OC(C)(C)C
Computed Properties
- Exact Mass: 286.03169Da
- Monoisotopic Mass: 286.03169Da
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 16
- Rotatable Bond Count: 3
- Complexity: 253
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.5
- Topological Polar Surface Area: 64.4?2
(2-AMINO-3-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| JIE DA WEI ( SHANG HAI ) YI YAO KE JI FA ZHAN Co., Ltd. | 20R0437-1g |
(2-Amino-3-bromo-phenyl)-carbamic acid tert-butyl ester |
954238-73-4 | 96% | 1g |
8463.46CNY | 2021-05-08 | |
| JIE DA WEI ( SHANG HAI ) YI YAO KE JI FA ZHAN Co., Ltd. | 20R0437-5g |
(2-Amino-3-bromo-phenyl)-carbamic acid tert-butyl ester |
954238-73-4 | 96% | 5g |
33904.74CNY | 2021-05-08 | |
| JIE DA WEI ( SHANG HAI ) YI YAO KE JI FA ZHAN Co., Ltd. | 20R0437-500mg |
(2-Amino-3-bromo-phenyl)-carbamic acid tert-butyl ester |
954238-73-4 | 96% | 500mg |
4655.75CNY | 2021-05-08 | |
| JIE DA WEI ( SHANG HAI ) YI YAO KE JI FA ZHAN Co., Ltd. | 20R0437-100mg |
(2-Amino-3-bromo-phenyl)-carbamic acid tert-butyl ester |
954238-73-4 | 96% | 100mg |
2756.14CNY | 2021-05-08 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1442389-100mg |
tert-Butyl (2-amino-3-bromophenyl)carbamate |
954238-73-4 | 98% | 100mg |
¥3351.00 | 2024-04-24 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1442389-500mg |
tert-Butyl (2-amino-3-bromophenyl)carbamate |
954238-73-4 | 98% | 500mg |
¥5659.00 | 2024-04-24 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1442389-1g |
tert-Butyl (2-amino-3-bromophenyl)carbamate |
954238-73-4 | 98% | 1g |
¥12014.00 | 2024-04-24 | |
| eNovation Chemicals LLC | Y1131137-500mg |
(2-Amino-3-bromo-phenyl)-carbamic acid tert-butyl ester |
954238-73-4 | 95% | 500mg |
$610 | 2025-02-25 | |
| eNovation Chemicals LLC | Y1131137-100mg |
(2-Amino-3-bromo-phenyl)-carbamic acid tert-butyl ester |
954238-73-4 | 95% | 100mg |
$370 | 2025-02-25 | |
| eNovation Chemicals LLC | Y1131137-1g |
(2-Amino-3-bromo-phenyl)-carbamic acid tert-butyl ester |
954238-73-4 | 95% | 1g |
$1115 | 2025-02-25 |
(2-AMINO-3-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER Related Literature
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P. K. Wawrzyniak,M. T. P. Beerepoot,H. J. M. de Groot,F. Buda Phys. Chem. Chem. Phys., 2011,13, 10270-10279
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Bo Cao,Yin Wei Chem. Commun., 2018,54, 2870-2873
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Hamid Heydari,Mohammad B. Gholivand New J. Chem., 2017,41, 237-244
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Xin Fu,Qing-rong Liang,Rong-guang Luo,Yan-shu Li,Xiao-ping Xiao,Lu-lu Yu,Wen-zhe Shan,Guang-qin Fan J. Mater. Chem. B, 2019,7, 3088-3099
Additional information on (2-AMINO-3-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER
Comprehensive Guide to (2-AMINO-3-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER (CAS No. 954238-73-4)
(2-AMINO-3-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER (CAS No. 954238-73-4) is a specialized organic compound widely used in pharmaceutical research and fine chemical synthesis. This bromo-substituted aromatic amine derivative plays a crucial role as an intermediate in the development of biologically active molecules. With the increasing demand for targeted drug discovery and small molecule therapeutics, this compound has gained significant attention from medicinal chemists worldwide.
The molecular structure of (2-AMINO-3-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER features both amino and carbamate functional groups, making it particularly valuable for structure-activity relationship studies. Researchers frequently utilize this compound in protease inhibitor development and kinase-targeted therapies, areas that have seen exponential growth in recent years due to advancements in precision medicine approaches.
In the context of current pharmaceutical trends, 954238-73-4 has become particularly relevant for cancer research applications. The compound's bromine substituent offers unique opportunities for cross-coupling reactions, a technique that has revolutionized modern drug discovery pipelines. Many researchers are investigating its potential in creating novel tyrosine kinase inhibitors, which represent one of the most searched categories in oncological drug development databases.
The tert-butyl carbamate (Boc) protecting group in (2-AMINO-3-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER provides excellent stability during synthetic transformations while allowing for selective deprotection when needed. This characteristic makes it invaluable for multi-step organic synthesis, especially in the construction of complex heterocyclic scaffolds that dominate current medicinal chemistry literature.
From a market perspective, the demand for 954238-73-4 has steadily increased alongside the growth of contract research organizations (CROs) and pharmaceutical outsourcing. Analytical data shows rising search volumes for this compound in connection with high-throughput screening and fragment-based drug design, reflecting its importance in modern drug discovery workflows.
The synthesis and handling of (2-AMINO-3-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER require specialized knowledge of amine protection strategies and aromatic substitution chemistry. Recent publications highlight its utility in creating allosteric modulators for various biological targets, addressing one of the most pressing challenges in drug development - achieving selectivity against closely related protein families.
Quality control of 954238-73-4 typically involves advanced analytical techniques such as HPLC purity analysis and mass spectrometry characterization. These methods ensure the compound meets the stringent requirements of pharmaceutical-grade intermediates, a critical factor for researchers who frequently search for "high-purity bromo aromatic compounds" in scientific databases.
Environmental and regulatory considerations for (2-AMINO-3-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER follow standard protocols for research chemicals. Proper storage conditions and handling procedures align with general laboratory safety practices for organic synthesis intermediates, making it accessible to qualified researchers worldwide without special restrictions.
Future applications of 954238-73-4 may expand into bioconjugation chemistry and proteolysis-targeting chimera (PROTAC) development, two rapidly growing areas that consistently rank high in pharmaceutical research search trends. Its unique combination of reactivity and protecting group chemistry positions it as a versatile building block for next-generation therapeutics.
For researchers seeking custom synthesis or bulk quantities of (2-AMINO-3-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER, it's essential to partner with suppliers who can provide comprehensive analytical data and structure confirmation. The compound's value in drug discovery justifies the need for rigorous quality standards throughout the supply chain.
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