- Synthesis of impurities of LansoprazoleLi, Wei; Chen, Shuai; Hao, Linghua; Wu, Song, Zhongguo Yaoxue Zazhi (Beijing, 2010, 45(6), 471-473
Cas no 953787-54-7 (Lansoprazole Sulfone N-Oxide)
Lansoprazole Sulfone N-Oxide structure
Product Name:Lansoprazole Sulfone N-Oxide
CAS No:953787-54-7
MF:C16H14F3N3O4S
MW:401.360272884369
CID:827234
PubChem ID:23656862
Update Time:2024-10-25
Lansoprazole Sulfone N-Oxide Chemical and Physical Properties
Names and Identifiers
-
- Lansoprazole Sulfone N-Oxide
- 2-(((1H-benzo[d]imidazol-2-yl)sulfonyl)methyl)-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine 1-oxide
- 2-[[[3-Methyl-1-oxido-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl]sulfonyl]-1H-benzimidazole
- 2-[[[3-Methyl-1-oxido-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole (ACI)
- 2-[[3-Methyl-1-oxido-4-(2,2,2-trifluoroethoxy)pyridin-1-ium-2-yl]methylsulfonyl]-1H-benzimidazole
- Lansoprazole Sulphone N-Oxide
- 2-(((3-Methyl-1-oxido-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfonyl)-1H-benzimidazole
- BCP31929
- 953787-54-7
- AKOS030255668
- RQCPAMTYJRPELQ-UHFFFAOYSA-N
- DTXSID40635355
- X9YP7UA99M
- 2-{[3-Methyl-1-oxo-4-(2,2,2-trifluoroethoxy)-1lambda~5~-pyridin-2-yl]methanesulfonyl}-1H-benzimidazole
- 2-(((1H-Benzo(d)imidazol-2-yl)sulfonyl)methyl)-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine 1-oxide
- 1H-Benzimidazole, 2-(((3-methyl-1-oxido-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfonyl)-
- UNII-X9YP7UA99M
- 2-[[[3-Methyl-1-oxido-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole
- F19224
- Lansoprazole Sulphone N-Oxide; Lansoprazole Sulfone N-Oxide
- 2-[[[3-METHYL-1-OXIDO-4-(2,2,2-TRIFLUOROETHOXY)-PYRIDIN-2-YL]METHYL]SULFONYL]-1H-BENZO[D]IMIDAZOLE
- LansoprazoleSulfoneN-Oxide
-
- Inchi： 1S/C16H14F3N3O4S/c1-10-13(22(23)7-6-14(10)26-9-16(17,18)19)8-27(24,25)15-20-11-4-2-3-5-12(11)21-15/h2-7H,8-9H2,1H3,(H,20,21)
- InChI Key： RQCPAMTYJRPELQ-UHFFFAOYSA-N
- SMILES： [O-][N+]1C(CS(C2NC3C(=CC=CC=3)N=2)(=O)=O)=C(C)C(OCC(F)(F)F)=CC=1
Computed Properties
- Exact Mass: 401.06571160g/mol
- Monoisotopic Mass: 401.06571160g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 8
- Heavy Atom Count: 27
- Rotatable Bond Count: 5
- Complexity: 613
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2
- Topological Polar Surface Area: 106?2
Experimental Properties
- Melting Point: 224-226°C
Lansoprazole Sulfone N-Oxide Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：Store at recommended temperature
Lansoprazole Sulfone N-Oxide Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | L175030-10mg |
Lansoprazole Sulfone N-Oxide |
953787-54-7 | 10mg |
$ 265.00 | 2023-09-07 | ||
| TRC | L175030-25mg |
Lansoprazole Sulfone N-Oxide |
953787-54-7 | 25mg |
$ 466.00 | 2023-09-07 | ||
| TRC | L175030-50mg |
Lansoprazole Sulfone N-Oxide |
953787-54-7 | 50mg |
$ 874.00 | 2023-09-07 | ||
| TRC | L175030-100mg |
Lansoprazole Sulfone N-Oxide |
953787-54-7 | 100mg |
$1584.00 | 2023-05-18 | ||
| Cooke Chemical | M7286358-1mg |
Lansoprazolesulfonen-oxide |
953787-54-7 | 95% | 1mg |
RMB 1895.20 | 2025-02-21 | |
| SHENG KE LU SI SHENG WU JI SHU | sc-211719-1mg |
Lansoprazole Sulfone N-Oxide, |
953787-54-7 | 1mg |
￥3234.00 | 2023-09-05 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-211719-1 mg |
Lansoprazole Sulfone N-Oxide, |
953787-54-7 | 1mg |
￥3,234.00 | 2023-07-10 | ||
| 1PlusChem | 1P005SJ8-5mg |
2-[[[3-METHYL-1-OXIDO-4-(2,2,2-TRIFLUOROETHOXY)-PYRIDIN-2-YL]METHYL]SULFONYL]-1H-BENZO[D]IMIDAZOLE |
953787-54-7 | ≥98% | 5mg |
$158.00 | 2024-04-19 | |
| 1PlusChem | 1P005SJ8-10mg |
2-[[[3-METHYL-1-OXIDO-4-(2,2,2-TRIFLUOROETHOXY)-PYRIDIN-2-YL]METHYL]SULFONYL]-1H-BENZO[D]IMIDAZOLE |
953787-54-7 | ≥98% | 10mg |
$265.00 | 2024-04-19 | |
| 1PlusChem | 1P005SJ8-25mg |
2-[[[3-METHYL-1-OXIDO-4-(2,2,2-TRIFLUOROETHOXY)-PYRIDIN-2-YL]METHYL]SULFONYL]-1H-BENZO[D]IMIDAZOLE |
953787-54-7 | ≥98% | 25mg |
$500.00 | 2024-04-19 |
Lansoprazole Sulfone N-Oxide Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: m-Chloroperbenzoic acid Solvents: Dichloromethane ; 0 °C; 1 h, cooled; 3 h, rt
1.2 Reagents: Sodium bicarbonate Solvents: Water ; pH 7 - 8
1.2 Reagents: Sodium bicarbonate Solvents: Water ; pH 7 - 8
Reference
Production Method 2
Reaction Conditions
1.1 Reagents: m-Chloroperbenzoic acid Solvents: Chloroform ; 45 min, -20 °C → -25 °C; 1 h, -25 °C; -25 °C → 0 °C; 1 h, 0 °C
1.2 Reagents: Acetic acid , Sodium hydroxide Solvents: Water ; pH 8, 0 °C
1.3 Reagents: Acetic acid Solvents: Methanol ; pH 7, 10 °C → 5 °C
1.2 Reagents: Acetic acid , Sodium hydroxide Solvents: Water ; pH 8, 0 °C
1.3 Reagents: Acetic acid Solvents: Methanol ; pH 7, 10 °C → 5 °C
Reference
- Synthesis and characterization of metabolites and potential impurities of lansoprazole, an antiulcerative drugReddy, Ganta Madhusudhan; Mukkanti, K.; Kumar, T. Laxmi; Babu, J. Moses; Reddy, Padi Pratap, Synthetic Communications, 2008, 38(20), 3477-3489
Production Method 3
Reaction Conditions
1.1 Reagents: m-Chloroperbenzoic acid Solvents: Dichloromethane ; 145 min, 0 °C; 15 min, 0 °C
Reference
- Efficient synthesis of N-oxide derivatives: Substituted 2-(2-(pyridyl-N-oxide)methylsulphinyl)benzimidazolesRay, Purna C.; Mittapelli, Vasantha; Rohatgi, Amit; Tyagi, Om Dutt, Synthetic Communications, 2007, 37(17), 2861-2868
Lansoprazole Sulfone N-Oxide Raw materials
Lansoprazole Sulfone N-Oxide Preparation Products
Lansoprazole Sulfone N-Oxide Related Literature
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Ni-Na Sun,Fengli Qu,Xiaobing Zhang,Shufang Zhang,Jinmao You Analyst, 2015,140, 1827-1831
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Suji Lee,Min Su Han Chem. Commun., 2021,57, 9450-9453
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4. An all-solid-state imprinted polymer-based potentiometric sensor for determination of bisphenol S?Rongning Liang,Tanji Yin,Ruiqing Yao,Wei Qin RSC Adv., 2016,6, 73308-73312
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Xin Fu,Qing-rong Liang,Rong-guang Luo,Yan-shu Li,Xiao-ping Xiao,Lu-lu Yu,Wen-zhe Shan,Guang-qin Fan J. Mater. Chem. B, 2019,7, 3088-3099
953787-54-7 (Lansoprazole Sulfone N-Oxide) Related Products
- 131926-99-3(Lansoprazole sulfone)
- 1329613-29-7(5-Hydroxy Lansoprazole Potassium Salt)
- 934294-22-1(Lansoprazole-d4 (benzimidazole-4,5,6,7-d4))
- 1083100-27-9(N-3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinylmethyl Lansoprazole Sulfide)
- 163119-30-0(Lansoprazole Sulfide N-Oxide)
- 213476-12-1(Lansoprazole N-Oxide)
- 138530-94-6((R)-Lansoprazole)
- 103577-45-3(Lansoprazole)
- 131926-98-2(1H-Benzimidazol-6-ol,2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-)
- 158812-85-2(Omeprazole Sulfone N-Oxide)
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