Production Method 1

95-01-2

95332-26-6

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Acetone ;  5 h, rt

Reference

Design, synthesis and docking study of 5-(substituted benzylidene)thiazolidine-2,4-dione derivatives as inhibitors of protein tyrosine phosphatase 1B

Wang, Zengtao; Liu, Zhiguo; Lee, Woojung; Kim, Su-Nam; Yoon, Goo; et al, Bioorganic & Medicinal Chemistry Letters, 2014, 24(15), 3337-3340

Production Method 2

95-01-2

95332-26-6

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Acetone ;  rt; 3 h, rt → reflux

Reference

Total synthesis of (+)-rutamarin

Zhang, Yi-Nan; Zhang, Shi-Lei; Ma, Lei; Zhang, Yu; Shen, Xu; et al, Advanced Synthesis & Catalysis, 2008, 350, 2373-2379

Production Method 3

95-01-2

95332-26-6

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Acetone ;  0 °C; 1 h, 0 °C; 0 °C → rt; 24 h, rt
1.2 Solvents: Water ;  0 °C

Reference

Total Synthesis of Caesalpinnone A

Liu, Zhigang; Meng, Yifei; Yuan, Pengrui; Wang, Zhengshen; Gao, Jin-Ming ; et al, Organic Letters, 2020, 22(2), 520-522

Production Method 4

95-01-2

95332-26-6

Reaction Conditions

1.1 Reagents: Diisopropylethylamine Solvents: Dichloromethane ;  0 °C; 15 min, 0 °C
1.2 16 h, rt
1.3 Reagents: Hydrochloric acid Solvents: Diethyl ether ,  Water

Reference

Preparation of [(biphenylyl)butenynyl]benzoates and analogs as retinoid receptor ligands

, European Patent Organization, , ,

Production Method 5

95-01-2

95332-26-6

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Acetone ;  0 °C; 2 h, reflux; reflux → rt

Reference

Synthesis and biological activity of flavane derivatives

He, Lan; Kong, E-Jing; Liu, Yu-Mei; An, Yu; Zhang, Wen-Sheng; et al, Chinese Journal of Chemistry, 2006, 24(3), 401-408

Production Method 6

95-01-2

95332-26-6

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Acetone ;  cooled; 1 h, 0 °C; 0 °C → rt; 24 h, rt

Reference

Biomimetic Syntheses and Antiproliferative Activities of Racemic, Natural (-), and Unnatural (+) Glyceollin I

Khupse, Rahul S.; Sarver, Jeffrey G.; Trendel, Jill A.; Bearss, Nicole R.; Reese, Michael D.; et al, Journal of Medicinal Chemistry, 2011, 54(10), 3506-3523

Production Method 7

95-01-2

95332-26-6

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Acetone ;  0 °C; 6 h, rt

Reference

Novel thiazolidinedione derivatives with anti-obesity effects: Dual action as PTP1B inhibitors and PPAR-γ activators

Bhattarai, Bharat Raj; Kafle, Bhooshan; Hwang, Ji-Sun; Ham, Seung Wook; Lee, Keun-Hyeung; et al, Bioorganic & Medicinal Chemistry Letters, 2010, 20(22), 6758-6763

Production Method 8

95-01-2

13057-17-5

95332-26-6

Reaction Conditions

1.1 Reagents: Diisopropylethylamine Solvents: Dichloromethane ,  Tetrahydrofuran ;  rt → 0 °C
1.2 0 °C → rt; 16 h, rt

Reference

N-Containing chromen-4-one derivatives for the treatment and prophylaxis of hepatitis B virus infection and their preparation

, World Intellectual Property Organization, , ,

Production Method 9

95-01-2

13057-17-5

95332-26-6

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Acetone ;  overnight, rt

Reference

Preparation of O-lactam substituted phenyl ethers as hemoglobin modulators

, United States, , ,

Production Method 10

95-01-2

95332-26-6

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Acetone ;  overnight, rt
1.2 Reagents: Water

Reference

Structure-activity relationships and key structural feature of pyridyloxybenzene-acylsulfonamides as new, potent, and selective peroxisome proliferator-activated receptor (PPAR) γ Agonists

Rikimaru, Kentaro; Wakabayashi, Takeshi; Abe, Hidenori; Tawaraishi, Taisuke; Imoto, Hiroshi; et al, Bioorganic & Medicinal Chemistry, 2012, 20(10), 3332-3358

Production Method 11

95-01-2

95332-26-6

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Acetone ;  4 h, rt

Reference

The first total synthesis of phebaclavin A and C

Zhang, Yu; Liu, Dong; Li, Yang; Cao, Xiao-Ping, Chinese Journal of Chemistry, 2005, 23(10), 1453-1456

Production Method 12

95-01-2

95332-26-6

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Acetone ;  24 h, rt

Reference

Synthesis of 6-methoxy-1-oxaspiro[4.5]deca-6,9-dien-8-one

Plourde, Guy L.; Fisher, Benjamin B., Molecules [online computer file], 2002, 7(2), 315-319

Production Method 13

95-01-2

13057-17-5

95332-26-6

Reaction Conditions

1.1 Reagents: Diisopropylethylamine Solvents: Dichloromethane ;  0 °C; 0 °C → rt; 12 h, rt
1.2 Reagents: Hydrochloric acid Solvents: Water ;  acidified, rt

Reference

Tandem Claisen Rearrangement/6-endo Cyclization Approach to Allylated and Prenylated Chromones

Schmidt, Bernd; Riemer, Martin; Schilde, Uwe, European Journal of Organic Chemistry, 2015, 2015(34), 7602-7611

Production Method 14

3970-21-6

95-01-2

95332-26-6

Reaction Conditions

1.1 Reagents: Diisopropylethylamine Solvents: Dichloromethane ;  5 min, rt; overnight, rt

Reference

Inhibitors of DNA polymerase β: Activity and mechanism

Gao, Zhijie; Maloney, David J.; Dedkova, Larisa M.; Hecht, Sidney M., Bioorganic & Medicinal Chemistry, 2008, 16(8), 4331-4340

Production Method 15

95-01-2

95332-26-6

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Acetone ;  0 °C; 0 °C → rt; 28 h, rt

Reference

A chiral pool approach for asymmetric syntheses of both antipodes of equol and sativan

Yalamanchili, Chinni; Chittiboyina, Amar G.; Chandra Kumar Rotte, Sateesh; Katzenellenbogen, John A.; Helferich, William G.; et al, Tetrahedron, 2018, 74(16), 2020-2029

Production Method 16

95-01-2

95332-26-6

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Acetone ;  cooled; 1 h, 0 °C; 0 °C → rt; 24 h, rt

Reference

Methods for synthesizing glycinols, glyceollins I and II, compositions of selected intermediates, and therapeutic uses thereof

, World Intellectual Property Organization, , ,

Production Method 17

95-01-2

95332-26-6

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Acetone ;  20 h, rt

Reference

Glucosylated near-infrared dye suitable for visualization targeted drug delivery

, China, , ,

Production Method 18

95-01-2

95332-26-6

Reaction Conditions

1.1 Reagents: Diisopropylethylamine Solvents: Dichloromethane ;  0 °C; 2 h, 0 °C

Reference

Design and synthesis of 3,3'-biscoumarin-based c-Met inhibitors

Xu, Jimin; Ai, Jing; Liu, Sheng; Peng, Xia; Yu, Linqian; et al, Organic & Biomolecular Chemistry, 2014, 12(22), 3721-3734

Production Method 19

95-01-2

95332-26-6

Reaction Conditions

1.1 Reagents: Diisopropylethylamine Solvents: Tetrahydrofuran ;  overnight, rt

Reference

Stable pharmaceutical compositions of pegylated carfilzomib compounds

, United States, , ,

Production Method 20

95-01-2

95332-26-6

Reaction Conditions

1.1 Reagents: Diisopropylethylamine Solvents: Tetrahydrofuran ;  overnight, rt

Reference

Preparation of pegylated carfilzomib compounds and prodrugs, their pharmaceutical compositions and methods and uses for treating cancers

, World Intellectual Property Organization, , ,

Benzaldehyde, 2-hydroxy-4-(methoxymethoxy)- Raw materials

• 2-Methoxyethoxymethyl chloride
• 2,4-Dihydroxybenzaldehyde
• Bromomethyl methyl ether

Benzaldehyde, 2-hydroxy-4-(methoxymethoxy)- Preparation Products

• Benzaldehyde, 2-hydroxy-4-(methoxymethoxy)- (95332-26-6)

• 1. Establishing empirical design rules of nucleic acid templates for the synthesis of silver nanoclusters with tunable photoluminescence and functionalities towards targeted bioimaging applications?
  Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932
• 2. Examination of deposit in commercial diluted phosphoric acid
  Analyst, 1880,5, 146-147
• 3. Fast synthesis of copper nanoclusters through the use of hydrogen peroxide additive and their application for the fluorescence detection of Hg2+ in water samples?
  Liao Xiaoqing,Li Ruiyi,Li Zaijun,Sun Xiulan,Wang Zhouping,Liu Junkang New J. Chem., 2015,39, 5240-5248
• 4. Establishing the accuracy of position-specific carbon isotope analysis of propane by GC-pyrolysis-GC-IRMS
  ChangjieLiu,PengLiu,XiaofengWang,XiaoqiangLi,JuskeHorita
• 5. Dissociative dynamics of O2 on Ag(110)?
  Ivor Lon?ari? Phys. Chem. Chem. Phys., 2015,17, 9436-9445

• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Aldehydes

• 13709-06-3(Benzaldehyde, 2,4-bis(methoxymethoxy)-)
• 73220-19-6(Benzaldehyde, 2-methoxy-6-(methoxymethoxy)-)
• 77354-97-3(Benzaldehyde, 2,2'-[methylenebis(oxy)]bis-)
• 5533-04-0(2-(Methoxymethoxy)-benzaldehyde)
• 342616-12-0(2,4-Dioxabicyclo[3.3.1]nona-1,1(9),3,5(9),5,7-hexaene-6-carboxaldehyde)
• 114628-32-9(Benzaldehyde, 2-methoxy-4-(methoxymethoxy)-)
• 61454-72-6(Benzaldehyde, 4,4'-[oxybis(methyleneoxy)]bis[2-methoxy-)
• 914399-70-5(Benzaldehyde, 2-hydroxy-4-(methoxymethoxy)-3-methyl-)
• 73220-20-9(Benzaldehyde, 5-methoxy-2-(methoxymethoxy)-)
• 124555-63-1(4-Methoxy-2-(MethoxyMethoxy)benzaldehyde)