Production Method 1

55414-45-4

953039-61-7

Reaction Conditions

1.1 Reagents: Manganese oxide (MnO2) Solvents: Chloroform ;  0 °C; 16 h, rt

Reference

Fused ring pyrimidine compound, intermediate, and preparation method, composition and use thereof

, World Intellectual Property Organization, , ,

Production Method 2

55414-45-4

953039-61-7

Reaction Conditions

1.1 Reagents: Manganese oxide (MnO2) Solvents: Chloroform ;  overnight, rt → 40 °C

Reference

Preparation of tricyclic heteroaryl-substituted quinoline and azaquinoline compounds as PAR4 inhibitors

, World Intellectual Property Organization, , ,

Production Method 3

55414-45-4

953039-61-7

Reaction Conditions

1.1 Reagents: Manganese oxide (MnO2) Solvents: Chloroform ;  overnight, rt → 40 °C

Reference

Preparation of bicyclic heteroaryl substituted compounds as PAR4 inhibitors

, World Intellectual Property Organization, , ,

Production Method 4

55414-45-4

953039-61-7

Reaction Conditions

1.1 Reagents: Manganese oxide (MnO2) Solvents: Chloroform ;  0 °C; 16 h, rt

Reference

Condensed-ring pyrimidylamino derivatives, preparation method therefor, and intermediate, pharmaceutical composition and applications in the treatment of cancer

, World Intellectual Property Organization, , ,

Production Method 5

55414-45-4

953039-61-7

Reaction Conditions

1.1 Reagents: Manganese oxide (MnO2) Solvents: Dichloromethane ;  12 h, rt

Reference

2-Arylaminoquinazolines as PDKI inhibitors and their preparation and use in the treatment of proliferative diseases

, World Intellectual Property Organization, , ,

Production Method 6

55414-45-4

953039-61-7

Reaction Conditions

1.1 Reagents: Manganese oxide (MnO2) Solvents: Dichloromethane ;  12 h, rt

Reference

Preparation of quinazolines for PDK1 inhibition

, World Intellectual Property Organization, , ,

2-Amino-3-bromo-5-fluorobenzaldehyde Raw materials

• 2-amino-3-bromo-5-fluoro-benzyl alcohol

2-Amino-3-bromo-5-fluorobenzaldehyde Preparation Products

• 2-Amino-3-bromo-5-fluorobenzaldehyde (953039-61-7)

• 1. Excellent lithium ion storage property of porous MnCo2O4 nanorods?
  Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
• 2. Fast synthesis of copper nanoclusters through the use of hydrogen peroxide additive and their application for the fluorescence detection of Hg2+ in water samples?
  Liao Xiaoqing,Li Ruiyi,Li Zaijun,Sun Xiulan,Wang Zhouping,Liu Junkang New J. Chem., 2015,39, 5240-5248
• 3. Evolution of dealloying induced strain in nanoporous gold crystals?
  Ross Harder,David C. Dunand,Ian McNulty Nanoscale, 2017,9, 5686-5693
• 4. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?
  Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139
• 5. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
  Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203

• 202865-77-8(2-bromo-4-fluoro-6-methyl-aniline)
• 105515-19-3(Ethanone, 1-(2-amino-3-bromo-5-fluorophenyl)-)
• 145123-24-6(2-Amino-3-bromobenzaldehyde)
• 1620239-30-6(2-Amino-4-bromo-5-fluorobenzaldehyde)
• 259269-84-6(2-Amino-3-bromo-5-fluorobenzoic acid)
• 953039-60-6(2-Amino-3-bromo-5-fluorobenzoic acid hydrobromide)
• 1379586-00-1(4-Amino-3-bromo-5-fluorobenzaldehyde)
• 151446-28-5(2-Amino-3-bromo-5-methylbenzaldehyde)
• 315188-30-8(2-amino-5-bromo-4-fluorobenzaldehyde)
• 906811-51-6(2-Amino-5-bromo-3-fluorobenzaldehyde)