Production Method 1

2009011-90-7

951626-38-3

Reaction Conditions

1.1 Reagents: Hydrochloric acid
1.2 Reagents: Sodium hydroxide

Reference

Route Design to Manufacture: Synthesis of the Heterocyclic Fragment of AZD5718 Using a Non-cryogenic Lithiation-Alkoxycarbonylation Reaction

Burns, Matthew ; Perkins, Dave; Chan, Lai C.; Pilling, Michael J.; Jawor-Baczynska, Anna; et al, Organic Process Research & Development, 2021, 25(4), 858-870

Production Method 2

2009011-91-8

951626-38-3

Reaction Conditions

1.1 Reagents: Sodium carbonate Solvents: 1,4-Dioxane ,  Water ;  3 h, rt

Reference

Further optimization of the M1 PAM VU0453595: Discovery of novel heterobicyclic core motifs with improved CNS penetration

Panarese, Joseph D.; Cho, Hykeyung P.; Adams, Jeffrey J.; Nance, Kellie D.; Garcia-Barrantes, Pedro M.; et al, Bioorganic & Medicinal Chemistry Letters, 2016, 26(15), 3822-3825

Production Method 3

951626-38-3

Reaction Conditions

Reference

Preparation of new benzimidazole pyridine derivatives for modulating SIK activity

, World Intellectual Property Organization, , ,

6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one Raw materials

• Ethyl 1-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-1H-pyrazole-5-carboxylate
• Ethyl 1-(2-aminoethyl)-1H-pyrazole-5-carboxylate

6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one Preparation Products

• 6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one (951626-38-3)

• 1. Excellent kinetics of single-phase Gd-doped ceria fuel electrodes in solid oxide cells?
  Andreas Nenning,Manuel Holzmann,Jürgen Fleig,Alexander K. Opitz Mater. Adv., 2021,2, 5422-5431
• 2. Dissociation of large gaseous serine clusters produces abundant protonated serine octamer
  Jacob S. Jordan,Evan R. Williams Analyst, 2021,146, 2617-2625
• 3. Evolution of cellulose into flexible conductive green electronics: a smart strategy to fabricate sustainable electrodes for supercapacitors
  Tengfei Yu,Yuehan Wu,Wei Li,Bin Li RSC Adv., 2014,4, 34134-34143
• 4. Estimation of activation energy for electroporation and pore growth rate in liquid crystalline and gel phases of lipid bilayers using molecular dynamics simulations?
  Amit Kumar Majhi,Subbarao Kanchi,V. Venkataraman,K. G. Ayappa,Prabal K. Maiti Soft Matter, 2015,11, 8632-8640
• 5. Fast synthesis of red Li3BaSrLn3(WO4)8:Eu3+ phosphors for white LEDs under near-UV excitation by a microwave-assisted solid state reaction method and photoluminescence studies
  Bo Wei,Zhenyu Liu,Chen Xie,Shu Yang,Wentao Tang,Aiwei Gu,Wing-Tak Wong,Ka-Leung Wong J. Mater. Chem. C, 2015,3, 12322-12327

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Carboxylic acid derivatives Carboxylic acid amides

• 1221278-38-1(4H,5H,6H,7H-pyrazolo1,5-apyrazine-2-carbaldehyde)
• 492423-46-8(N-cycloheptyl-1-ethyl-1H-pyrazole-5-carboxamide)
• 1029721-02-5(4-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazine-2-carboxylic acid)
• 1133065-96-9(3,4-Dihydropyrazino[1,2-b]indazol-1(2H)-one)
• 2060026-96-0(5-methyl-4H,5H,6H,7H-pyrazolo1,5-apyrazin-4-one)
• 957299-23-9(1-methyl-N-[(1-methyl-1H-pyrazol-5-yl)methyl]-1H-pyrazole-5-carboxamide)
• 1301714-05-5(2-methyl-4H,5H,6H,7H-pyrazolo1,5-apyrazin-4-one)
• 586354-45-2(3H-Pyrazino[1,2-b]pyrazolo[3,4-g]indazol-6(7H)-one, 8,9-dihydro-)
• 442870-29-3(N-(2-aminoethyl)-1-methyl-1H-pyrazole-5-carboxamide)
• 1005580-78-8(1-methyl-N-[3-(3-methyl-1H-pyrazol-1-yl)propyl]-1H-pyrazole-5-carboxamide)