Cas no 947013-57-2 (4-Methyl-2-pyrrolidin-1-yl-1,3-thiazole-5-carboxylic acid)
4-Methyl-2-pyrrolidin-1-yl-1,3-thiazole-5-carboxylic acid is a heterocyclic compound featuring a thiazole core substituted with a pyrrolidine ring and a carboxylic acid functional group. This structure imparts unique physicochemical properties, making it valuable in medicinal chemistry and drug development. The compound exhibits potential as a versatile intermediate for synthesizing biologically active molecules, particularly in the design of kinase inhibitors and other therapeutic agents. Its rigid thiazole scaffold enhances binding affinity to target proteins, while the pyrrolidine moiety contributes to improved solubility and pharmacokinetic profiles. The carboxylic acid group allows for further derivatization, enabling the creation of amides, esters, or other derivatives for structure-activity relationship studies. Its well-defined synthetic route ensures high purity and reproducibility for research applications.
947013-57-2 structure
Product Name:4-Methyl-2-pyrrolidin-1-yl-1,3-thiazole-5-carboxylic acid
CAS No:947013-57-2
MF:C9H12N2O2S
MW:212.268780708313
CID:3047008
PubChem ID:42481078
Update Time:2025-07-02
4-Methyl-2-pyrrolidin-1-yl-1,3-thiazole-5-carboxylic acid Chemical and Physical Properties
Names and Identifiers
-
- 4-Methyl-2-pyrrolidin-1-yl-thiazole-5-carboxylic acid
- 4-Methyl-2-pyrrolidin-1-yl-1,3-thiazole-5-carboxylic acid
- 4-Methyl-2-(pyrrolidin-1-yl)thiazole-5-carboxylic acid
- F2165-0012
- 4-methyl-2-(pyrrolidin-1-yl)-1,3-thiazole-5-carboxylic acid
- SCHEMBL13787617
- STK727316
- AKOS000303069
- 4-Methyl-2-(pyrrolidin-1-yl)thiazole-5-carboxylicacid
- 947013-57-2
- BBL011824
- VS-03059
-
- MDL： MFCD09996837
- Inchi： 1S/C9H12N2O2S/c1-6-7(8(12)13)14-9(10-6)11-4-2-3-5-11/h2-5H2,1H3,(H,12,13)
- InChI Key： BDGXYESYCPEQEQ-UHFFFAOYSA-N
- SMILES： S1C(C(O)=O)=C(C)N=C1N1CCCC1
Computed Properties
- Exact Mass: 212.06194880g/mol
- Monoisotopic Mass: 212.06194880g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 14
- Rotatable Bond Count: 2
- Complexity: 231
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.2
- Topological Polar Surface Area: 81.7?2
4-Methyl-2-pyrrolidin-1-yl-1,3-thiazole-5-carboxylic acid Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 059091-2g |
4-Methyl-2-pyrrolidin-1-yl-thiazole-5-carboxylic acid |
947013-57-2 | 2g |
￡598.00 | 2022-03-01 | ||
| Fluorochem | 059091-1g |
4-Methyl-2-pyrrolidin-1-yl-thiazole-5-carboxylic acid |
947013-57-2 | 1g |
￡372.00 | 2022-03-01 | ||
| TRC | M256146-100mg |
4-methyl-2-pyrrolidin-1-yl-1,3-thiazole-5-carboxylic acid |
947013-57-2 | 100mg |
$ 70.00 | 2022-06-04 | ||
| TRC | M256146-500mg |
4-methyl-2-pyrrolidin-1-yl-1,3-thiazole-5-carboxylic acid |
947013-57-2 | 500mg |
$ 250.00 | 2022-06-04 | ||
| TRC | M256146-1g |
4-methyl-2-pyrrolidin-1-yl-1,3-thiazole-5-carboxylic acid |
947013-57-2 | 1g |
$ 365.00 | 2022-06-04 | ||
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 033500-500mg |
4-Methyl-2-pyrrolidin-1-yl-thiazole-5-carboxylic acid |
947013-57-2 | 500mg |
2600.0CNY | 2021-07-13 | ||
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 033500-500mg |
4-Methyl-2-pyrrolidin-1-yl-thiazole-5-carboxylic acid |
947013-57-2 | 500mg |
2600CNY | 2021-05-07 | ||
| Chemenu | CM530615-1g |
4-Methyl-2-(pyrrolidin-1-yl)thiazole-5-carboxylic acid |
947013-57-2 | 97% | 1g |
$285 | 2023-01-01 | |
| Chemenu | CM530615-5g |
4-Methyl-2-(pyrrolidin-1-yl)thiazole-5-carboxylic acid |
947013-57-2 | 97% | 5g |
$857 | 2023-01-01 | |
| Crysdot LLC | CD11006078-5g |
4-Methyl-2-(pyrrolidin-1-yl)thiazole-5-carboxylic acid |
947013-57-2 | 97% | 5g |
$856 | 2024-07-19 |
4-Methyl-2-pyrrolidin-1-yl-1,3-thiazole-5-carboxylic acid Related Literature
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Guiying Zhang,Maosheng Cheng,Yanni Li,Keliang Liu,Lifeng Cai Chem. Commun., 2013,49, 11086-11088
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Jason Wan Lab Chip, 2020,20, 4528-4538
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Joo Chuan Yeo,Kenry Lab Chip, 2016,16, 4082-4090
-
Xinhuan Wang,Shuangfei Cai,Cui Qi Analyst, 2017,142, 2500-2506
-
Manickam Bakthadoss,Tadiparthi Thirupathi Reddy,Vishal Agarwal,Duddu S. Sharada Chem. Commun., 2022,58, 1406-1409
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