Production Method 1

946-89-4

947-04-6

Reaction Conditions

1.1 Catalysts: Zinc chloride Solvents: Toluene ;  100 °C
1.2 Catalysts: Thionyl chloride Solvents: Toluene ;  30 min, 100 °C; 25 min, 105 °C

Reference

Method for producing lactam compound by Beckmann rearrangement of cycloalkanone oxime

, World Intellectual Property Organization, , ,

Production Method 2

946-89-4

947-04-6

Reaction Conditions

1.1 Catalysts: Cyanuric chloride Solvents: Isopropylcyclohexane ;  10 min, 113 °C

Reference

Preparation of amides from ketoximes

, Germany, , ,

Production Method 3

946-89-4

947-04-6

Reaction Conditions

1.1 Solvents: Benzonitrile ;  60 min, 190 °C

Reference

Gas and liquid phase catalytic Beckmann rearrangement of oximes to produce lactams

, United States, , ,

Production Method 4

946-89-4

947-04-6

Reaction Conditions

1.1 Reagents: Thionyl chloride Catalysts: Zinc chloride Solvents: Toluene ;  1 h, 103 °C

Reference

Process for production of amide or lactam

, World Intellectual Property Organization, , ,

Production Method 5

946-89-4

947-04-6

Reaction Conditions

1.1 Catalysts: Phosphorus pentoxide ,  Zinc chloride Solvents: Acetonitrile ,  Toluene ;  1 h, 100 °C

Reference

Manufacturing method for laurolactam

, World Intellectual Property Organization, , ,

Production Method 6

946-89-4

947-04-6

Reaction Conditions

1.1 Catalysts: Methanesulfonic acid ,  Phosphorus pentoxide ,  Zinc chloride Solvents: Toluene ;  1 h, 110 °C

Reference

Production of laurolactam with low energy consumption

, Japan, , ,

Production Method 7

947-04-6

Reaction Conditions

1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Methanol ;  4 h, rt

Reference

Ring closing metathesis approach to produce precursors of nylon 11, 12, and 13 from oleic acid

, World Intellectual Property Organization, , ,

Production Method 8

946-89-4

947-04-6

Reaction Conditions

1.1 Catalysts: Aluminum isopropoxide ,  Silica ,  Phosphoric acid Solvents: Water ;  1.5 h, rt
1.2 Catalysts: Dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride Solvents: Water ;  rt
1.3 Reagents: Triethylamine Solvents: Water ;  rt; 1 h, rt
1.4 Catalysts: Silica Solvents: Water ;  rt; 1.5 h, rt
1.5 Solvents: Benzonitrile ;  360 min, 130 °C

Reference

Hierarchical aluminophosphates as catalysts for the beckmann rearrangement

, United States, , ,

Production Method 9

946-89-4

947-04-6

Reaction Conditions

1.1 Catalysts: Cyclododecanone, O-azacyclotridec-1-en-2-yloxime, hydrochloride (1:1) Solvents: Toluene ;  rt; 1 h, 105 °C

Reference

Preparation of cyclododecanone-O-azacyclotridecene-2-yloxime, its hydrochloride salt, and laurolactam

, World Intellectual Property Organization, , ,

Production Method 10

946-89-4

947-04-6

Reaction Conditions

1.1 Catalysts: Cyanuric chloride ,  Zinc chloride Solvents: Toluene ,  Cyclopentyl methyl ether ;  1 h, 95 °C

Reference

Preparation of laurolactam by Beckmann rearrangement of cyclododecanone oxime in high yield

, Japan, , ,

Production Method 11

946-89-4

947-04-6

Reaction Conditions

1.1 Catalysts: Thionyl chloride Solvents: Toluene ;  5 min, rt
1.2 Catalysts: Zinc chloride Solvents: Toluene ;  100 °C; 60 min, 100 °C

Reference

Method for the preparation of amide compound

, World Intellectual Property Organization, , ,

Production Method 12

946-89-4

947-04-6

Reaction Conditions

1.1 Reagents: Benzonitrile ,  Zinc chloride Catalysts: Cyanuric chloride Solvents: Toluene ;  1 h, 110 °C

Reference

Preparation of amides or lactams by catalytic Beckmann rearrangement of oximes

, Japan, , ,

Production Method 13

946-89-4

947-04-6

Reaction Conditions

1.1 Catalysts: Cyanuric chloride ;  3 h, 160 °C

Reference

Manufacture of laurolactam by Beckmann rearrangement reaction of cyclododecanone oxime

, Japan, , ,

Production Method 14

946-89-4

947-04-6

Reaction Conditions

1.1 Reagents: Hydrochloric acid Catalysts: Cyclododecanone, 1,1′-[O,O′-(6-chloro-1,3,5-triazine-2,4-diyl)dioxime] Solvents: Acetonitrile ,  Water ;  1 h, 78 °C

Reference

Production method and Beckmann rearrangement catalyst for producing a cyclic lactam compound

, Japan, , ,

Production Method 15

946-89-4

947-04-6

Reaction Conditions

1.1 Solvents: 1,2,4-Trimethylbenzene ;  4 h, 393 °C

Reference

Nanosized and delayered zeolitic materials for the liquid-phase Beckmann rearrangement of cyclododecanone oxime

Botella, P.; Corma, A.; Iborra, S.; Monton, R.; Rodriguez, I.; et al, Journal of Catalysis, 2007, 250(1), 161-170

Production Method 16

946-89-4

947-04-6

Reaction Conditions

1.1 Catalysts: Hexachlorocyclotriphosphazene Solvents: 1,1,1,3,3,3-Hexafluoro-2-propanol ;  6 h, 70 °C

Reference

Beckmann Rearrangement of Ketoximes to Lactams by Triphosphazene Catalyst

Hashimoto, Masaharu; Obora, Yasushi; Sakaguchi, Satoshi; Ishii, Yasutaka, Journal of Organic Chemistry, 2008, 73(7), 2894-2897

Production Method 17

1074-51-7

946-89-4

947-04-6

935-30-8

Reaction Conditions

1.1 Catalysts: Cyanuric chloride Solvents: Cyclooctane ;  0.5 h, 113 °C

Reference

Preparation of amides from ketoximes

, Germany, , ,

Azacyclotridecan-2-one Raw materials

• N-cyclooctylidenehydroxylamine
• cyclododecanone, oxime

Azacyclotridecan-2-one Preparation Products

• Azonan-2-one (935-30-8)
• Azacyclotridecan-2-one (947-04-6)

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• Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Macrolactams Macrolactams
• Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Macrolactams
• Solvents and Organic Chemicals Organic Compounds Amines/Sulfonamides

• 25747-65-3(Azacyclododecan-2-one,homopolymer)
• 38207-56-6(Hexanediamide,N1,N6-didocosyl-)
• 56403-09-9(1,8-Diaza-2,9-diketocyclotetradecane)
• 1009-89-8(1-azacycloundecan-2-one)
• 10264-28-5(Hexanamide, N-butyl-)
• 67391-64-4(Decanediamide, N,N'-bis(6-aminohexyl)-)
• 10264-25-2(Pentanamide, N-hexyl-)
• 31827-03-9(Decanediamide,N1,N10-dihexyl-)
• 35081-84-6(Decanediamide,N1,N10-dioctadecyl-)
• 33422-43-4(Dodecanamide, N-dodecyl-)