Production Method 1

951127-35-8

945217-56-1

Reaction Conditions

1.1 Reagents: Hydrochloric acid Solvents: Water ;  1.5 h, rt

Reference

Preparation of phenylheteroarylpiperidinamine derivatives for use as dipeptidyl peptidase-IV inhibitors

, World Intellectual Property Organization, , ,

Production Method 2

945217-56-1

Reaction Conditions

Reference

Heterocyclic compounds as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes

, United States, , ,

Production Method 3

1988686-33-4

945217-56-1

Reaction Conditions

1.1 Reagents: Hydrochloric acid Solvents: Ethanol ,  Water ;  3 h, 90 °C

Reference

Preparation of substituted six-membered heterocyclic amine compounds as DPP-IV inhibitors

, China, , ,

Production Method 4

951127-35-8

945217-56-1

Reaction Conditions

1.1 Reagents: Hydrochloric acid Solvents: Methanol ;  12 h, rt
1.2 Reagents: Ammonium hydroxide ,  Ammonia Solvents: Methanol ,  Water

Reference

Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes, hyperglycemia, and obesity

, United States, , ,

Production Method 5

951127-35-8

945217-56-1

Reaction Conditions

1.1 Reagents: Hydrochloric acid Solvents: Water ;  1.5 h, rt

Reference

Preparation of pyrrolopyrazolylaminocyclohexanes and related compounds as dipeptidylpeptidase-IV (DPP-IV) inhibitors for the treatment or prevention of diabetes

, World Intellectual Property Organization, , ,

3-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole Raw materials

• 1,1-Dimethylethyl 2,6-dihydro-3-methyl-2-[[2-(trimethylsilyl)ethoxy]methyl]pyrrolo[3,4-c]pyrazole-5(4H)-carboxylate
• tert-butyl 3-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-5-carboxylate

3-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole Preparation Products

• 3-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole (945217-56-1)

• 1. Excellent humidity sensor based on ultrathin HKUST-1 nanosheets?
  Qiaoe Wang,Meiling Lian,Xiaowen Zhu,Xu Chen RSC Adv., 2021,11, 192-197
• 2. Evolution of important glucosinolates in three common Brassica vegetables during their processing into vegetable powder and in vitro gastric digestion
  Nan Fu,Naphaporn Chiewchan,Xiao Dong Chen Food Funct., 2020,11, 211-220
• 3. Fast-pulsing NMR techniques for the detection of weak interactions: successful natural abundance probe of hydrogen bonds in peptides?
  Amandine Altmayer-Henzien,Valérie Declerck,David J. Aitken,Ewen Lescop,Denis Merlet,Jonathan Farjon Org. Biomol. Chem., 2013,11, 7611-7615
• 4. Establishing new scaling relations on two-dimensional MXenes for CO2 electroreduction?
  Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
• 5. Distinct correlation between (CN2)x units and pores: a low-cost method for predesigned wide range control of micropore size of porous carbon?
  Xiaotong Feng,Lei Bian,Jie Ma,Lei Zhou,Xiayan Wang,Guangsheng Guo,Qiaosheng Pu Chem. Commun., 2019,55, 3963-3966

• 933750-52-8(3-methyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole)
• 306747-98-8(1H-Pyrazole-4-methanamine,N-ethyl-3,5-dimethyl-)
• 769895-06-9(1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole)
• 1117915-55-5(1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole hydrochloride)
• 6573-19-9(2,4,5,6-tetrahydro-Pyrrolo[3,4-c]pyrazole)
• 919347-92-5((3,5-dimethyl-1H-pyrazol-4-yl)methyl(methyl)amine)
• 1523617-96-0(3-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole dihydrochloride)
• 157327-47-4(1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole dihydrochloride)
• 1270030-00-6(2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carbonitrile)
• 1337879-50-1(N1-((3,5-dimethyl-1H-pyrazol-4-yl)methyl)ethane-1,2-diamine trihydrochloride)