- Fluorine-substituted indazole compounds as soluble guanylate cyclase inhibitors and their preparation, World Intellectual Property Organization, , ,
Cas no 944904-38-5 (7-Fluoro-3-iodo-1H-indazole)
7-Fluoro-3-iodo-1H-indazole structure
Product Name:7-Fluoro-3-iodo-1H-indazole
CAS No:944904-38-5
MF:C7H4FIN2
MW:262.022936820984
MDL:MFCD10696806
CID:1027715
PubChem ID:53408492
Update Time:2024-10-25
7-Fluoro-3-iodo-1H-indazole Chemical and Physical Properties
Names and Identifiers
-
- 7-Fluoro-3-iodo-1H-indazole
- 7-fluoro-3-iodo-2H-indazole
- 7-Fluoro-3-iodoindazole
- 1H-Indazole, 7-fluoro-3-iodo-
- NZLJQLITHWOQBC-UHFFFAOYSA-N
- FCH1400949
- AB58221
- AX8168577
- Y5677
- 7-Fluoro-3-iodo-1H-indazole (ACI)
- 944904-38-5
- SY037467
- DTXSID10696312
- J-519250
- SCHEMBL14158301
- P10935
- AKOS015950376
- CS-0050028
- DA-35654
- MFCD10696806
- EN300-6775533
- AS-50710
-
- MDL： MFCD10696806
- Inchi： 1S/C7H4FIN2/c8-5-3-1-2-4-6(5)10-11-7(4)9/h1-3H,(H,10,11)
- InChI Key： NZLJQLITHWOQBC-UHFFFAOYSA-N
- SMILES： FC1C2=C(C(=NN2)I)C=CC=1
Computed Properties
- Exact Mass: 261.94000
- Monoisotopic Mass: 261.94032g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 11
- Rotatable Bond Count: 0
- Complexity: 155
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 28.7
- XLogP3: 2.3
Experimental Properties
- PSA: 28.68000
- LogP: 2.30660
7-Fluoro-3-iodo-1H-indazole Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM150249-1g |
7-Fluoro-3-iodo-1H-indazole |
944904-38-5 | 95%+ | 1g |
$*** | 2023-03-31 | |
| Chemenu | CM150249-5g |
7-Fluoro-3-iodo-1H-indazole |
944904-38-5 | 95%+ | 5g |
$137 | 2024-07-19 | |
| TRC | F599153-50mg |
7-Fluoro-3-iodo-1H-indazole |
944904-38-5 | 50mg |
$ 50.00 | 2022-06-04 | ||
| TRC | F599153-100mg |
7-Fluoro-3-iodo-1H-indazole |
944904-38-5 | 100mg |
$ 65.00 | 2022-06-04 | ||
| TRC | F599153-500mg |
7-Fluoro-3-iodo-1H-indazole |
944904-38-5 | 500mg |
$ 115.00 | 2022-06-04 | ||
| JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd. | 45R0458-1g |
7-Fluoro-3-iodo-1H-indazole |
944904-38-5 | 96% | 1g |
661.47CNY | 2021-05-08 | |
| JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd. | 45R0458-5g |
7-Fluoro-3-iodo-1H-indazole |
944904-38-5 | 96% | 5g |
2187.95CNY | 2021-05-08 | |
| JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd. | 45R0458-25g |
7-Fluoro-3-iodo-1H-indazole |
944904-38-5 | 96% | 25g |
8353.22CNY | 2021-05-08 | |
| CHENG DOU FEI BO YI YAO Technology Co., Ltd. | FB05602-25g |
7-fluoro-3-iodo-1h-indazole |
944904-38-5 | 95% | 25g |
$885 | 2023-09-07 | |
| Fluorochem | 223412-1g |
7-Fluoro-3-iodo-1H-indazole |
944904-38-5 | 95% | 1g |
￡90.00 | 2022-02-28 |
7-Fluoro-3-iodo-1H-indazole Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Boron trifluoride etherate , Isoamyl nitrite Solvents: Tetrahydrofuran ; 0 °C; -10 °C; 30 min, -10 °C
1.2 Reagents: Sodium iodide Solvents: Acetone ; 0 °C; 30 min, rt
1.2 Reagents: Sodium iodide Solvents: Acetone ; 0 °C; 30 min, rt
Reference
Production Method 2
Reaction Conditions
1.1 Reagents: Potassium hydroxide , Iodine Solvents: Dimethylformamide ; 20 min, 50 °C
1.2 Reagents: Sodium bisulfite Solvents: Water ; 2 h, rt
1.2 Reagents: Sodium bisulfite Solvents: Water ; 2 h, rt
Reference
- Indazole and pyrrolopyridine derivatives as serotonin-4 receptor agonists and their preparation and pharmaceutical use thereof, Japan, , ,
Production Method 3
Reaction Conditions
1.1 Reagents: Potassium hydroxide , Iodine Solvents: Dimethylformamide ; 0 °C; 1 h, 25 °C
Reference
- Preparation of fused heteroaryl compounds for treatment of tauopathies, World Intellectual Property Organization, , ,
Production Method 4
Reaction Conditions
1.1 Reagents: Potassium hydroxide , Iodine Solvents: Dimethylformamide ; 1 h, rt
Reference
- Preparation of heterocycle compounds for the treatment of allergic disease, Japan, , ,
Production Method 5
Reaction Conditions
1.1 Reagents: Potassium hydroxide , Iodine Solvents: Dimethylformamide ; 1 h, rt
Reference
- Preparation of heterocyclic compounds having PGD2 receptor antagonist activity, World Intellectual Property Organization, , ,
7-Fluoro-3-iodo-1H-indazole Raw materials
7-Fluoro-3-iodo-1H-indazole Preparation Products
7-Fluoro-3-iodo-1H-indazole Related Literature
-
Chengbin Yang,Hing Lun Tsang,Pui Man Lau,Ken-Tye Yong,Ho Pui Ho,Siu Kai Kong Analyst, 2017,142, 3579-3587
-
James D. Kirkham,Patrick M. Delaney,George J. Ellames,Eleanor C. Row,Joseph P. A. Harrity Chem. Commun., 2010,46, 5154-5156
-
Kui Wu,Zhihua Yang,Shilie Pan Dalton Trans., 2015,44, 19856-19864
944904-38-5 (7-Fluoro-3-iodo-1H-indazole) Related Products
- 1000342-06-2(4,7-difluoro-3-iodo-1h-indazole)
- 2432848-78-5(6-Bromo-7-fluoro-3-iodo-1H-indazole)
- 887567-92-2(3,4-Diiodo-6-fluoro-(1H)indazole)
- 1352398-23-2(5-bromo-7-fluoro-3-iodo-1H-indazole)
- 885522-07-6(6-fluoro-3-iodo-1H-indazole)
- 518990-32-4(4-Fluoro-3-iodo-1H-indazole)
- 887568-05-0(3,6-Diiodo-4-fluoroindazole)
- 858629-06-8(5-Fluoro-3-iodo-1H-indazole)
- 1000341-94-5(4-chloro-7-fluoro-3-iodo-1h-indazole)
- 887567-79-5(4,6-Difluoro-3-iodo-1H-indazole)
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